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巴西干旱气候地区登革热传播的时空分析。

A spatio-temporal analysis of dengue spread in a Brazilian dry climate region.

机构信息

Centro Universitário Senai Cimatec - Salvador, Bahia, Brazil.

VALORIZA - Research Center for Endogenous Resources Valorization, Portalegre, Portugal.

出版信息

Sci Rep. 2021 Jun 4;11(1):11892. doi: 10.1038/s41598-021-91306-z.

DOI:10.1038/s41598-021-91306-z
PMID:34088931
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8178350/
Abstract

We investigated the relation between the spread, time scale, and spatial arrangement of dengue in Bahia, a Brazilian dry climate region, for the period 2000 to 2009. The degree of cross-correlation is calculated for 15 economic regions. We propose a multiscale statistical analysis to datasets of dengue cases in order to verify the effect of infection dispersal on the economic regions from the metropolitan region of Salvador. Our empirical results support a significant and persistent cross-correlation between most regions, reinforcing the idea that economic regions or climatic conditions are non-statistically significant in the spread of dengue in the State of Bahia. Our main contribution lies in the cross-correlation results revealing multiple aspects related to the propagation of dengue in dry climate regions.

摘要

我们研究了巴西干旱气候地区巴伊亚州 2000 年至 2009 年期间登革热的传播、时间尺度和空间分布之间的关系。我们为 15 个经济区计算了交叉相关系数。我们对登革热病例数据集提出了一种多尺度统计分析,以验证从萨尔瓦多大都市区感染扩散对经济区的影响。我们的实证结果支持大多数地区之间存在显著且持久的交叉相关性,这进一步证实了经济区或气候条件在巴伊亚州登革热传播中并不具有统计学意义。我们的主要贡献在于交叉相关结果揭示了与干旱气候地区登革热传播相关的多个方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/ea13d05b1a81/41598_2021_91306_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/58e9a535b229/41598_2021_91306_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/380427d7c36f/41598_2021_91306_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/5f1bb5b05403/41598_2021_91306_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/6ad7d385f82e/41598_2021_91306_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/39e72550ab10/41598_2021_91306_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/ea13d05b1a81/41598_2021_91306_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/58e9a535b229/41598_2021_91306_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/380427d7c36f/41598_2021_91306_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/5f1bb5b05403/41598_2021_91306_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/6ad7d385f82e/41598_2021_91306_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/39e72550ab10/41598_2021_91306_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b82a/8178350/ea13d05b1a81/41598_2021_91306_Fig6_HTML.jpg

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Serotype-specific detection of dengue viruses in a nonstructural protein 1-based enzyme-linked immunosorbent assay validated with a multi-national cohort.基于非结构蛋白 1 的酶联免疫吸附试验对登革热病毒进行血清型特异性检测,该试验经多国家队列验证。
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