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胸腔硬膜外增强术后康复(ERAS)路径用于漏斗胸的 Nuss 修复,缩短了住院时间并减少了静脉阿片类药物的抢救使用。

Thoracic epidural-based Enhanced Recovery After Surgery (ERAS) pathway for Nuss repair of pectus excavatum shortened length of stay and decreased rescue intravenous opiate use.

机构信息

Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, GRB-425, Boston, MA, 02114, USA.

Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA, USA.

出版信息

Pediatr Surg Int. 2021 Sep;37(9):1191-1199. doi: 10.1007/s00383-021-04934-x. Epub 2021 Jun 4.

Abstract

BACKGROUND

PCA- and block-based enhanced recovery after surgery (ERAS) pathways have been shown to decrease hospital length of stay (HLOS) and opiate use following Nuss Repair for Pectus Excavatum (NRPE). No thoracic epidural-based ERAS pathway has demonstrated similar benefits.

METHODS

In this pre-post single-center study, data were retrospectively collected for patients ≤ 21 years undergoing NRPE from May 2015 to August 2019. Univariate and multivariate methods were used to evaluate whether implementation of a thoracic epidural-based ERAS in April 2017 was associated with HLOS, opiate use, or pain scores.

RESULTS

There were 110 patients: 35 pre- and 75 post-ERAS. HLOS decreased from median 4.8 (1.1) to 3.3 (0.6) days with ERAS (p < 0.001). Use of rescue intravenous opiates decreased from 35.3% pre- to 9.3% with ERAS (p = 0.013). When adjusted for baseline characteristics, ERAS was associated with a 1.3 ± 0.2 day decrease in HLOS and 0.188 times the odds of rescue intravenous opiate use (p = 0.011).

CONCLUSIONS

Pain scores, ED visits, and readmissions did not change with ERAS (p > 0.05). Implementation of a thoracic epidural-based ERAS following NRPE was associated with decreased HLOS and need for any rescue intravenous opiates without a change in pain scores, ED visits, or readmission.

摘要

背景

PCA 和基于块的术后加速康复(ERAS)路径已被证明可以减少漏斗胸 Nuss 修复术(NRPE)后患者的住院时间(HLOS)和阿片类药物的使用。尚无基于胸段硬膜外的 ERAS 路径显示出类似的益处。

方法

在这项单中心前后对照研究中,回顾性收集了 2015 年 5 月至 2019 年 8 月期间接受 NRPE 的≤21 岁患者的数据。采用单因素和多因素方法评估 2017 年 4 月实施基于胸段硬膜外的 ERAS 是否与 HLOS、阿片类药物使用或疼痛评分相关。

结果

共纳入 110 例患者:ERAS 前 35 例,ERAS 后 75 例。ERAS 后 HLOS 从中位数 4.8(1.1)天降至 3.3(0.6)天(p<0.001)。ERAS 后使用急救静脉阿片类药物的比例从 35.3%降至 9.3%(p=0.013)。在调整了基线特征后,ERAS 与 HLOS 减少 1.3±0.2 天和急救静脉阿片类药物使用的几率降低 0.188 倍相关(p=0.011)。

结论

ERAS 后疼痛评分、急诊就诊和再入院率没有变化(p>0.05)。NRPE 后实施基于胸段硬膜外的 ERAS 与 HLOS 缩短和任何急救静脉阿片类药物的需求减少相关,而疼痛评分、急诊就诊或再入院率没有变化。

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