Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, GRB-425, Boston, MA, 02114, USA.
Department of Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA, USA.
Pediatr Surg Int. 2021 Sep;37(9):1191-1199. doi: 10.1007/s00383-021-04934-x. Epub 2021 Jun 4.
PCA- and block-based enhanced recovery after surgery (ERAS) pathways have been shown to decrease hospital length of stay (HLOS) and opiate use following Nuss Repair for Pectus Excavatum (NRPE). No thoracic epidural-based ERAS pathway has demonstrated similar benefits.
In this pre-post single-center study, data were retrospectively collected for patients ≤ 21 years undergoing NRPE from May 2015 to August 2019. Univariate and multivariate methods were used to evaluate whether implementation of a thoracic epidural-based ERAS in April 2017 was associated with HLOS, opiate use, or pain scores.
There were 110 patients: 35 pre- and 75 post-ERAS. HLOS decreased from median 4.8 (1.1) to 3.3 (0.6) days with ERAS (p < 0.001). Use of rescue intravenous opiates decreased from 35.3% pre- to 9.3% with ERAS (p = 0.013). When adjusted for baseline characteristics, ERAS was associated with a 1.3 ± 0.2 day decrease in HLOS and 0.188 times the odds of rescue intravenous opiate use (p = 0.011).
Pain scores, ED visits, and readmissions did not change with ERAS (p > 0.05). Implementation of a thoracic epidural-based ERAS following NRPE was associated with decreased HLOS and need for any rescue intravenous opiates without a change in pain scores, ED visits, or readmission.
PCA 和基于块的术后加速康复(ERAS)路径已被证明可以减少漏斗胸 Nuss 修复术(NRPE)后患者的住院时间(HLOS)和阿片类药物的使用。尚无基于胸段硬膜外的 ERAS 路径显示出类似的益处。
在这项单中心前后对照研究中,回顾性收集了 2015 年 5 月至 2019 年 8 月期间接受 NRPE 的≤21 岁患者的数据。采用单因素和多因素方法评估 2017 年 4 月实施基于胸段硬膜外的 ERAS 是否与 HLOS、阿片类药物使用或疼痛评分相关。
共纳入 110 例患者:ERAS 前 35 例,ERAS 后 75 例。ERAS 后 HLOS 从中位数 4.8(1.1)天降至 3.3(0.6)天(p<0.001)。ERAS 后使用急救静脉阿片类药物的比例从 35.3%降至 9.3%(p=0.013)。在调整了基线特征后,ERAS 与 HLOS 减少 1.3±0.2 天和急救静脉阿片类药物使用的几率降低 0.188 倍相关(p=0.011)。
ERAS 后疼痛评分、急诊就诊和再入院率没有变化(p>0.05)。NRPE 后实施基于胸段硬膜外的 ERAS 与 HLOS 缩短和任何急救静脉阿片类药物的需求减少相关,而疼痛评分、急诊就诊或再入院率没有变化。