通过荧光光度法测定的角膜上皮通透性与日戴型隐形眼镜佩戴情况

Corneal epithelial permeability and daily contact lens wear as determined by fluorophotometry.

作者信息

Boets E P, van Best J A, Boot J P, Oosterhuis J A

机构信息

Department of Ophthalmology, Leiden University Hospital, The Netherlands.

出版信息

Curr Eye Res. 1988 May;7(5):511-4. doi: 10.3109/02713688809031805.

DOI:10.3109/02713688809031805

PMID:3409717

Abstract

The condition of the corneal epithelium of 57 non-, 18 soft-, 29 gas-permeable- and 26 hard contact lens-wearing eyes was investigated by fluorophotometric determination of the corneal epithelial permeability. The mean permeability values for non-, soft-, gas-permeable- and hard contact lens-wearing eyes were 0.040 nm/s +/- 0.017 SD, 0.024 nm/s +/- 0.009 SD, 0.028 nm/s +/- 0.017 SD and 0.044 nm/s +/- 0.020 SD, respectively. The mean permeability values for soft and gas-permeable contact lens-wearing eyes were significantly lower than that for non contact lens-wearing eyes (-40%, p less than 0.001 and -30%, p less than 0.005); no significant difference was found between the mean values for hard and non contact lens-wearing eyes (p = 0.38).

摘要

通过荧光光度法测定角膜上皮通透性，对57只未佩戴隐形眼镜、18只佩戴软性隐形眼镜、29只佩戴透气硬性隐形眼镜和26只佩戴硬性隐形眼镜的眼睛的角膜上皮状况进行了研究。未佩戴隐形眼镜、佩戴软性隐形眼镜、佩戴透气硬性隐形眼镜和佩戴硬性隐形眼镜的眼睛的平均通透性值分别为0.040 nm/s±0.017标准差、0.024 nm/s±0.009标准差、0.028 nm/s±0.017标准差和0.044 nm/s±0.020标准差。佩戴软性和透气硬性隐形眼镜的眼睛的平均通透性值显著低于未佩戴隐形眼镜的眼睛（分别降低40%，p<0.001和降低30%，p<0.005）；佩戴硬性隐形眼镜和未佩戴隐形眼镜的眼睛的平均值之间未发现显著差异（p=0.38）。