ELSAN, Clinique Saint Michel, Centre Chirurgical de l'Obésité (CCO), 83100, Toulon, France.
Department of Digestive and Bariatric Surgery, Clinica Madonna della Salute, 45014, Porto Viro, Italy.
Obes Surg. 2021 Aug;31(8):3468-3475. doi: 10.1007/s11695-021-05455-1. Epub 2021 Jun 7.
The purpose of this study was to evaluate the efficacy and safety of the OAGB at least 10 years after surgery.
We retrospectively reviewed our prospectively collected data on consecutive morbid patients with obesity receiving OAGB from January 2005 to December 2007.
A total of 385 patients met the inclusion criteria. The mean follow-up was 149 months. Of all patients, 52% underwent OAGB as a primary procedure and 48% as a revisional procedure. At the 10-year follow-up, the mean body mass index (BMI) was 30.7 ± 11.8, the mean %TWL was 33.4 ± 10.6, and the mean %EWL was 64.1 ± 24.6. We did not find a significant statistical difference in terms of weight loss between primary OAGB and secondary OAGB. In total, 43% of patients achieved a %EWL greater than 75%, while 29% of the patients had an EWL% that was below 50%. All of the comorbidities related to obesity showed a high improvement or fully resolved. Early complications occurred in 9 patients (2.3%), while the overall rate of late complications was 17.1%. Nineteen patients (4.9%) developed an ulcer at the gastrojejunal anastomosis level, nine patients (2.3%) were re-hospitalized for major malnutrition, thirty-eight patients (9.8%) showed a postoperative biliary reflux, and five patients (2.7%) experienced severe anemia, which required several hospitalizations for iron I.V. supplementation.
According to results of the present study, we believe that OAGB has shown to be a technique with a reasonable balance between long-term efficacy and undesirable sequelae.
本研究旨在评估 OAGB 术后至少 10 年的疗效和安全性。
我们回顾性分析了 2005 年 1 月至 2007 年 12 月连续接受 OAGB 治疗的肥胖症患者的前瞻性收集数据。
共有 385 名患者符合纳入标准。平均随访时间为 149 个月。所有患者中，52%的患者首次手术采用 OAGB，48%的患者采用翻修手术。在 10 年随访时，患者平均体重指数（BMI）为 30.7±11.8，平均 %TWL 为 33.4±10.6，平均 %EWL 为 64.1±24.6。我们未发现初次 OAGB 和二次 OAGB 之间在减重方面有显著的统计学差异。总的来说，43%的患者实现了 EWL%大于 75%，而 29%的患者 EWL%小于 50%。所有与肥胖相关的合并症均得到了高度改善或完全缓解。9 例（2.3%）患者发生早期并发症，总晚期并发症发生率为 17.1%。19 例（4.9%）患者发生胃空肠吻合口溃疡，9 例（2.3%）患者因严重营养不良再次住院，38 例（9.8%）患者出现术后胆汁反流，5 例（2.7%）患者发生严重贫血，需要多次住院静脉补铁。
根据本研究结果，我们认为 OAGB 是一种长期疗效和不良后果之间具有合理平衡的技术。
