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Detection of , a Presumptive Ancestor, in a Plasmid from a Linezolid-Resistant Enterococcus gallinarum Isolate.在一株耐利奈唑胺的鹑鸡肠球菌分离株的质粒中检测到一种推测的祖先。
Antimicrob Agents Chemother. 2021 Jul 16;65(8):e0069521. doi: 10.1128/AAC.00695-21.
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Co-occurrence of multiple plasmid-borne linezolid resistance genes-optrA, cfr, poxtA2 and cfr(D) in an Enterococcus faecalis isolate from retail meat.零售肉中分离的屎肠球菌携带多种质粒介导的利奈唑胺耐药基因(optrA、cfr、poxtA2 和 cfr(D))。
J Antimicrob Chemother. 2023 Jul 5;78(7):1637-1643. doi: 10.1093/jac/dkad142.
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Linezolid-resistant Enterococcus gallinarum isolate of swine origin carrying cfr, optrA and poxtA genes.耐林可霉素粪肠球菌的猪源分离株，携带 cfr、optrA 和 poxtA 基因。
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Linezolid Resistance Genes in Enterococci Isolated from Sediment and Zooplankton in Two Italian Coastal Areas.从两个意大利沿海地区的沉积物和浮游动物中分离出的肠球菌中的利奈唑胺耐药基因。
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Linezolid-Resistant Enterococcus faecalis of Chicken Origin Harbored Chromosome-Borne and Plasmid-Borne , (D), and Genes.鸡源耐利奈唑酮屎肠球菌携带染色体和质粒携带, (D), 和 基因。
Microbiol Spectr. 2023 Jun 15;11(3):e0274122. doi: 10.1128/spectrum.02741-22. Epub 2023 Mar 30.
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Interregional spread in Spain of linezolid-resistant Enterococcus spp. isolates carrying the optrA and poxtA genes.西班牙耐林可霉素肠球菌属分离株中携带 optrA 和 poxtA 基因的区际传播。
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Detection of the Gene Among Polyclonal Linezolid-Susceptible Isolates of Recovered from Community Patients.检测来自社区患者恢复期的多药(linezolid)敏感分离株中的 基因。
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Genomic insights into linezolid-resistant Enterococci revealed its evolutionary diversity and poxtA copy number heterogeneity.基因组学研究揭示了耐利奈唑烷肠球菌的进化多样性和 poxtA 拷贝数异质性。
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Identification of plasmids co-carrying cfr(D)/optrA and cfr(D2)/poxtA linezolid resistance genes in two Enterococcus avium isolates from swine brain.从猪脑分离的两株鹑鸡肠球菌中发现同时携带 cfr(D)/optrA 和 cfr(D2)/poxtA 基因的质粒。
Vet Microbiol. 2023 Jul;282:109749. doi: 10.1016/j.vetmic.2023.109749. Epub 2023 Apr 24.

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Genomic Characterization and Phylogenetic Analysis of Linezolid-Resistant Enterococcus from the Nostrils of Healthy Hosts Identifies Zoonotic Transmission.从健康宿主鼻腔中分离出的耐利奈唑烷肠球菌的基因组特征和系统发育分析表明存在人畜共患病传播。
Curr Microbiol. 2024 Jun 14;81(8):225. doi: 10.1007/s00284-024-03737-2.
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Clin Microbiol Rev. 2024 Jun 13;37(2):e0012123. doi: 10.1128/cmr.00121-23. Epub 2024 Mar 11.
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Linezolid-Resistant Enterococcus faecalis of Chicken Origin Harbored Chromosome-Borne and Plasmid-Borne , (D), and Genes.鸡源耐利奈唑酮屎肠球菌携带染色体和质粒携带, (D), 和 基因。
Microbiol Spectr. 2023 Jun 15;11(3):e0274122. doi: 10.1128/spectrum.02741-22. Epub 2023 Mar 30.
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Prevalence and Genetic Analysis of Resistance Mechanisms of Linezolid-Nonsusceptible Enterococci in a Tertiary Care Hospital Examined via Whole-Genome Sequencing.通过全基因组测序检测三级护理医院中耐利奈唑胺肠球菌耐药机制的患病率及基因分析
Antibiotics (Basel). 2022 Nov 14;11(11):1624. doi: 10.3390/antibiotics11111624.
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Persistence of transferable oxazolidinone resistance genes in enterococcal isolates from a swine farm in China.中国某猪场肠球菌分离株中可转移恶唑烷酮耐药基因的持久性
Front Microbiol. 2022 Oct 10;13:1010513. doi: 10.3389/fmicb.2022.1010513. eCollection 2022.
6
Faecal carriage of enterococci harbouring oxazolidinone resistance genes among healthy humans in the community in Switzerland.瑞士社区健康人群中产 oxazolidinone 耐药基因的肠球菌粪便携带情况。
J Antimicrob Chemother. 2022 Sep 30;77(10):2779-2783. doi: 10.1093/jac/dkac260.
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Plasmid Fusion and Recombination Events That Occurred during Conjugation of -Carrying Plasmids in Enterococci.质粒融合和重组事件在肠球菌中携带质粒的共轭时发生。
Microbiol Spectr. 2022 Feb 23;10(1):e0150521. doi: 10.1128/spectrum.01505-21. Epub 2022 Jan 19.

本文引用的文献

1
Characterization of oxazolidinone and phenicol resistance genes in non-clinical enterococcal isolates from Korea.韩国非临床肠球菌分离株中恶唑烷酮和氯霉素耐药基因的特征。
J Glob Antimicrob Resist. 2021 Mar;24:363-369. doi: 10.1016/j.jgar.2021.01.009. Epub 2021 Jan 28.
2
Detection of Oxazolidinone Resistance Genes and Characterization of Genetic Environments in Enterococci of Swine Origin, Italy.意大利猪源肠球菌中恶唑烷酮耐药基因的检测及遗传环境特征分析
Microorganisms. 2020 Dec 17;8(12):2021. doi: 10.3390/microorganisms8122021.
3
Detection of the Phenicol-Oxazolidinone Resistance Gene in and from Food-Producing Animals during 2008-2018 in Korea.2008 - 2018年韩国产肉动物及其产品中氯霉素-恶唑烷酮耐药基因的检测
Microorganisms. 2020 Nov 23;8(11):1839. doi: 10.3390/microorganisms8111839.
4
Linezolid-resistant (Tn6246::fexB-poxtA) Enterococcus faecium strains colonizing humans and bovines on different continents: similarity without epidemiological link.耐(linezolid) （Tn6246::fexB-poxtA）肠球菌粪肠球菌株定植在不同大陆的人类和牛：无流行病学关联的相似性。
J Antimicrob Chemother. 2020 Sep 1;75(9):2416-2423. doi: 10.1093/jac/dkaa227.
5
Interregional spread in Spain of linezolid-resistant Enterococcus spp. isolates carrying the optrA and poxtA genes.西班牙耐林可霉素肠球菌属分离株中携带 optrA 和 poxtA 基因的区际传播。
Int J Antimicrob Agents. 2020 Jun;55(6):105977. doi: 10.1016/j.ijantimicag.2020.105977. Epub 2020 Apr 22.
6
Linezolid resistance in Enterococcus faecium and Enterococcus faecalis from hospitalized patients in Ireland: high prevalence of the MDR genes optrA and poxtA in isolates with diverse genetic backgrounds.爱尔兰住院患者屎肠球菌和粪肠球菌的利奈唑胺耐药性：具有不同遗传背景的分离株中高流行的多药耐药基因 optrA 和 poxtA。
J Antimicrob Chemother. 2020 Jul 1;75(7):1704-1711. doi: 10.1093/jac/dkaa075.
7
Ceftazidime-Avibactam Resistance Associated with Increased Gene Copy Number Mediated by pKpQIL Plasmid Derivatives in Sequence Type 258 .头孢他啶-阿维巴坦耐药与 258 型序列型中由 pKpQIL 质粒衍生物介导的基因拷贝数增加有关。
Antimicrob Agents Chemother. 2020 Mar 24;64(4). doi: 10.1128/AAC.01816-19.
8
Identification of a poxtA- and cfr-carrying multiresistant Enterococcus hirae strain.
J Antimicrob Chemother. 2020 Feb 1;75(2):482-484. doi: 10.1093/jac/dkz449.
9
Detection in Greece of a clinical Enterococcus faecium isolate carrying the novel oxazolidinone resistance gene poxtA.在希腊检测到一株携带新型恶唑烷酮抗性基因poxtA的临床粪肠球菌分离株。
J Antimicrob Chemother. 2019 Aug 1;74(8):2461-2462. doi: 10.1093/jac/dkz155.
10
Characterization of poxtA, a novel phenicol-oxazolidinone-tetracycline resistance gene from an MRSA of clinical origin.从临床来源的耐甲氧西林金黄色葡萄球菌中发现的新型氯霉素-恶唑烷酮-四环素耐药基因 poxtA 的特征。
J Antimicrob Chemother. 2018 Jul 1;73(7):1763-1769. doi: 10.1093/jac/dky088.

Detection of , a Presumptive Ancestor, in a Plasmid from a Linezolid-Resistant Enterococcus gallinarum Isolate.

作者信息

Baccani Ilaria, Antonelli Alberto, Di Pilato Vincenzo, Coppi Marco, Di Maggio Tiziana, Spinicci Michele, Villagran Ana Liz, Revollo Carmen, Bartoloni Alessandro, Rossolini Gian Maria

机构信息

Department of Experimental and Clinical Medicine, University of Florencegrid.8404.8, Florence, Italy.

Microbiology and Virology Unit, Careggi University Hospital, Florence, Italy.

出版信息

Antimicrob Agents Chemother. 2021 Jul 16;65(8):e0069521. doi: 10.1128/AAC.00695-21.

DOI:10.1128/AAC.00695-21
PMID:34097480
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8284432/
Abstract
摘要