Department of Psychology, "Sapienza" University of Rome, Rome, Italy; Cognitive and Motor Rehabilitation and Neuroimaging Unit, IRCCS Santa Lucia, Rome, Italy.
Department of Psychology, "Sapienza" University of Rome, Rome, Italy; Cognitive and Motor Rehabilitation and Neuroimaging Unit, IRCCS Santa Lucia, Rome, Italy; PhD Program in Behavioral Neuroscience, Sapienza University of Rome, Rome, Italy.
Neurosci Biobehav Rev. 2021 Aug;127:928-945. doi: 10.1016/j.neubiorev.2021.06.012. Epub 2021 Jun 6.
It has been proposed that declarative memory evolved from spatial navigation, with episodic memory having its roots in mechanisms of egocentric navigation and semantic memory in those of allocentric navigation; however, whether these brain networks actually overlap is still unclear. Using Activation Likelihood Estimation, we assessed the correspondence between brain correlates of spatial navigation (SN) and autobiographical memory (AM), further testing whether neural substrates of episodic memory (EAM) and egocentric navigation, and those of semantic memory (SAM) and map-like navigation, coincide. SN and AM commonly activated the parahippocampal gyrus and middle hippocampus, posterior cingulate cortex and right angular gyrus, but also involved distinct brain regions. Similarly, EAM and egocentric navigation, besides sharing a network involving the right angular gyrus, bilateral posterior cingulate and parahippocampal gyrus, activated distinct brain regions; no region was commonly activated by SAM and allocentric navigation. We discuss findings in the light of theories on the relation between navigation and memory, and propose a new theoretical perspective, which takes into account the dynamic nature of navigational processes.
有人提出，陈述性记忆是从空间导航演变而来的，情景记忆的根源在于自我中心导航的机制，语义记忆的根源在于非自我中心导航的机制；然而，这些大脑网络实际上是否重叠尚不清楚。我们使用激活似然估计来评估空间导航 (SN) 和自传体记忆 (AM) 的大脑相关物之间的对应关系，进一步测试情景记忆 (EAM) 和自我中心导航的神经基质，以及语义记忆 (SAM) 和类似地图的导航的神经基质是否一致。SN 和 AM 通常激活海马旁回和海马中部、后扣带皮层和右角回，但也涉及不同的大脑区域。同样，EAM 和自我中心导航，除了共享一个涉及右角回、双侧后扣带和海马旁回的网络外，还激活了不同的大脑区域；SAM 和非自我中心导航没有共同激活的区域。我们根据导航和记忆之间关系的理论来讨论这些发现，并提出了一种新的理论观点，该观点考虑到了导航过程的动态性质。
