Center for Brain Disorders and Cognitive Science, Shenzhen University, Shenzhen, PR China; Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.
Department of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA; Department of Psychological Sciences, University of Connecticut, Storrs, CT, USA; Department of Cognition, Emotion, and Methods in Psychology, Faculty of Psychology, University of Vienna, Vienna, Austria; Brain and Language Lab, Cognitive Science Hub, University of Vienna, Austria; Dept of Behavioral and Cognitive Biology, Faculty of Life Sciences, University of Vienna, Austria; Department of Psychology, Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland.
Cortex. 2021 Aug;141:262-279. doi: 10.1016/j.cortex.2021.02.033. Epub 2021 May 8.
Numerous studies have consistently reported functional activation of the cerebellum during reading tasks, especially in the right cerebellar hemisphere. However, it remains unclear whether this region is also involved in reading during the earliest stages of reading acquisition. Here, we investigated whether and how the cerebellum contributes to reading acquisition. We tested 80 5-6-year-old kindergarteners, who performed a visual word matching task during which functional MRI (fMRI) data were collected. We found that bilateral cerebellar hemispheres were significantly activated during visual word processing. Moreover, activation of left cerebellar lobule VII extending to lobule VIII negatively and significantly correlated with current reading ability, whereas activation of right cerebellar lobule VII extending to lobule VIII significantly and positively correlated with future reading ability. Functional decoding via functional connectivity patterns further revealed that left and right cerebellar lobules connected with different cerebral cortex regions. Our results suggest a division of labor between the left and right cerebellar lobules in beginning readers.
许多研究一致报告了小脑在阅读任务中的功能激活，尤其是在右小脑半球。然而，目前尚不清楚该区域是否也参与了阅读的早期习得过程。在这里，我们研究了小脑是否以及如何参与阅读习得。我们测试了 80 名 5-6 岁的幼儿园儿童，他们在执行视觉单词匹配任务期间收集了功能磁共振成像 (fMRI) 数据。我们发现，双侧小脑半球在视觉单词处理过程中被显著激活。此外，延伸至小脑叶 VIII 的左侧小脑叶 VII 的激活与当前的阅读能力呈负相关，而延伸至小脑叶 VIII 的右侧小脑叶 VII 的激活与未来的阅读能力呈正相关。通过功能连接模式进行的功能解码进一步揭示了左侧和右侧小脑叶与不同的大脑皮层区域相连。我们的研究结果表明，在初学者中，左、右小脑叶之间存在分工。
