DeMatteis Cardiovascular Institute, St. Francis Hospital & Heart Center, Roslyn, NY, USA.
EuroIntervention. 2021 Jun 11;17(2):e105-e123. doi: 10.4244/EIJ-D-21-00089.
Optical coherence tomography (OCT) has been increasingly utilised to guide percutaneous coronary intervention (PCI). Despite the diagnostic utility of OCT, facilitated by its high resolution, the impact of intracoronary OCT on clinical practice has thus far been limited. Difficulty in transitioning from intravascular ultrasound (IVUS), complex image interpretation, lack of a standardised algorithm for PCI guidance, and paucity of data from prospective clinical trials have contributed to the modest adoption. Herein, we provide a comprehensive up-do-date overview on the utility of OCT in coronary artery disease, including technical details, device set-up, simplified OCT image interpretation, recognition of the imaging artefacts, and an algorithmic approach for using OCT in PCI guidance. We discuss the utility of OCT in acute coronary syndromes, provide a summary of the clinical trial data, list the work in progress, and discuss the future directions.
光学相干断层扫描(OCT)已越来越多地用于指导经皮冠状动脉介入治疗(PCI)。尽管 OCT 分辨率高,具有诊断价值,但迄今为止,其对临床实践的影响仍然有限。从血管内超声(IVUS)转换的困难、复杂的图像解释、缺乏 PCI 指导的标准化算法以及前瞻性临床试验数据的缺乏都导致了其应用的局限性。本文全面介绍了 OCT 在冠状动脉疾病中的应用,包括技术细节、设备设置、简化的 OCT 图像解释、成像伪影的识别以及 OCT 在 PCI 指导中的算法方法。我们讨论了 OCT 在急性冠状动脉综合征中的应用,总结了临床试验数据,列出了正在进行的工作,并讨论了未来的方向。