经气管导管行正压通气的需早产儿产房内潮气量测量-可行性研究。

Tidal volume measurements in the delivery room in preterm infants requiring positive pressure ventilation via endotracheal tube-feasibility study.

机构信息

Division of Newborn Medicine, Department of Pediatrics, University of Massachusetts Medical School-Baystate, Springfield, MA, USA.

Epidemiology and Biostatistics Research Core, Office of Research, University of Massachusetts Medical School-Baystate, Springfield, MA, USA.

出版信息

J Perinatol. 2021 Aug;41(8):1930-1935. doi: 10.1038/s41372-021-01113-7. Epub 2021 Jun 10.

DOI:10.1038/s41372-021-01113-7

PMID:34112962

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8191447/

Abstract

OBJECTIVE

Current delivery room (DR) resuscitation utilizes pressure-limited devices without tidal volume (TV) measurements. Clinicians use chest expansion as a surrogate, which is a poor indicator of TV. TV in early life can be highly variable due to rapidly changing lung compliance. Our objectives were to assess feasibility of measuring TV in DR, and to report the generated TV in intubated patients.

STUDY DESIGN

Prospective, observational, feasibility study in infants <32 weeks GA and intubated in DR. TV was measured using a respiratory function monitor.

RESULT

Ten infants with mean GA 23.9(±1.5) weeks and mean BW 618.5(±155) gram were included. Total of 178 min (mean 17.8 min/patient) with 8175 individual breaths (mean 817.5 breaths/patient) were analyzed. Goal TV of 4-6 ml/kg was provided 23.5% of times with high TV (>6 ml/kg) provided 47.7% of times.

CONCLUSION

TV measurement in DR is feasible. It is associated with high intra and inter-patient variability.

摘要

目的

目前产房（DR）复苏采用限压型设备，不测量潮气量（TV）。临床医生使用胸廓扩张作为替代指标，但这是 TV 的一个很差的指标。由于肺顺应性的快速变化，早期生命中的 TV 可能会有很大的差异。我们的目标是评估在 DR 中测量 TV 的可行性，并报告气管插管患者的生成 TV。

研究设计

这是一项在<32 周胎龄和在 DR 中气管插管的婴儿中进行的前瞻性、观察性、可行性研究。使用呼吸功能监测仪测量 TV。

结果

共纳入 10 名平均胎龄为 23.9（±1.5）周、平均体重为 618.5（±155）克的婴儿。总共分析了 178 分钟（平均每位患者 17.8 分钟）和 8175 次呼吸（平均每位患者 817.5 次）。目标 TV 为 4-6ml/kg 的次数占 23.5%，高 TV（>6ml/kg）的次数占 47.7%。