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评估由耐抗菌药物细菌引起的动物疾病的特设方法。

Ad hoc method for the assessment of animal diseases caused by bacteria resistant to antimicrobials.

作者信息

Nielsen Søren Saxmose, Bicout Dominique Joseph, Calistri Paolo, Canali Elisabetta, Drewe Julian Ashley, Garin-Bastuji Bruno, Gonzales Rojas Jose Luis, Gortazar Schmidt Christian, Herskin Mette, Michel Virginie, Miranda Chueca Miguel Angel, Padalino Barbara, Pasquali Paolo, Roberts Helen Clare, Sihvonen Liisa Helena, Spoolder Hans, Stahl Karl, Velarde Antonio, Viltrop Arvo, Winckler Christoph, Dewulf Jeroen, Guardabassi Luca, Hilbert Friederike, Mader Rodolphe, Smith Peter, Aznar Inmaculada, Baldinelli Francesca, Alvarez Julio

出版信息

EFSA J. 2021 Jun 3;19(6):e06645. doi: 10.2903/j.efsa.2021.6645. eCollection 2021 Jun.

Abstract

The European Commission requested EFSA assess antimicrobial-resistant bacteria responsible for animal transmissible diseases, with a view to listing such pathogens for European Union action. This Scientific Opinion addresses the ad hoc method developed: (i) to give a global state of play as regards resistant animal pathogens that cause transmissible animal diseases, (ii) to identify the most relevant bacteria in the EU and (iii) to summarise their actual or potential animal health impact, and to perform their assessment for being listed and categorised according to the criteria of Articles 7, 5, 9 and 8 within the Animal Health Law (AHL) framework. An extensive literature review is carried out to give the global state of play of selected resistant bacteria that constitute a threat to animal health (i). An expert judgement procedure, based on the outcome of the literature review, is applied to identify which among those bacteria subjected to the literature review are the 'most relevant' in the European Union (ii). Their animal health impact in the European Union and their assessment for being listed and categorised according to the AHL framework will follow the 'ad hoc method for the assessment on listing and categorisation of animal diseases within the framework of the Animal Health Law' that EFSA has developed in the past (iii). The assessment of (i) and (ii) is addressed in distinct scientific opinions that are published separately by animal species of interest (dogs and cats, horses, pigs, poultry, cattle, small ruminants, rabbits and aquatic animal species). The assessment of (iii) is addressed in distinct scientific opinions and published separately by the animal pathogen.

摘要

欧盟委员会要求欧洲食品安全局评估导致动物传染病的抗菌药物耐药细菌,以期列出此类病原体以便欧盟采取行动。本科学意见阐述了所制定的特别方法:(i)说明导致动物传染病的耐药动物病原体的总体情况,(ii)确定欧盟最相关的细菌,以及(iii)总结它们对动物健康的实际或潜在影响,并根据《动物卫生法》(AHL)框架内第7、5、9和8条的标准对其进行评估以列入清单并分类。开展了广泛的文献综述以说明对动物健康构成威胁的选定耐药细菌的总体情况(i)。基于文献综述结果,采用专家判断程序来确定接受文献综述的细菌中哪些在欧盟是“最相关的”(ii)。它们对欧盟动物健康的影响以及根据AHL框架进行列入清单和分类的评估将遵循欧洲食品安全局过去制定的“动物卫生法框架内动物疾病清单和分类评估特别方法”(iii)。(i)和(ii)的评估在不同的科学意见中阐述,并按感兴趣的动物种类(狗和猫、马、猪、家禽、牛、小反刍动物、兔子和水生动物种类)分别发布。(iii)的评估在不同的科学意见中阐述,并按动物病原体分别发布。

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本文引用的文献

1
Guidance on Uncertainty Analysis in Scientific Assessments.
EFSA J. 2018 Jan 24;16(1):e05123. doi: 10.2903/j.efsa.2018.5123. eCollection 2018 Jan.
2

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