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韩国一项为期 1 年的随访研究:住院吸烟干预参与者中吸烟复发的模式和预测因素。

Patterns and predictors of smoking relapse among inpatient smoking intervention participants: a 1-year follow-up study in Korea.

机构信息

Center for Tobacco Control Research, Chungnam National University, Daejeon, Korea.

Daejeon‧Sejong Tobacco Control Center, Daejeon, Korea.

出版信息

Epidemiol Health. 2021;43:e2021043. doi: 10.4178/epih.e2021043. Epub 2021 Jun 9.

Abstract

OBJECTIVES

This study aimed to identify relapse patterns in smokers who participated in an inpatient treatment program and to investigate factors related to relapse.

METHODS

The participants comprised 463 smokers who participated in an inpatient treatment operated by the Daejeon Tobacco Control Center from 2015 to 2018. Participants received high-intensity smoking cessation intervention for 5 consecutive days, including pharmacotherapy and behavioral support, and continued with follow-up for 1 year to determine whether they maintained smoking cessation after discharge from inpatient treatment. Kaplan-Meier and Cox proportional hazard models were used in the analysis.

RESULTS

Participants' relapse rate within 1 year was 72.8%, and 59.8% of participants smoked again within 6 months after participation. A higher number of counseling sessions was significantly associated with a lower risk of relapse (hazard ratio [HR], 0.23; 95% confidence interval [CI], 0.17 to 0.32 for ≥9 vs. ≤5 counseling sessions). Conversely, higher relapse rates were significantly associated with the use of nicotine replacement therapy (NRT) (HR, 1.91; 95% CI, 1.43 to 2.55 for use vs. no use), and higher levels of baseline expired carbon monoxide (CO) (HR, 1.58; 95% CI, 1.21 to 2.06 for expired CO concentrations of 10-19 ppm vs. expired CO concentrations <10 ppm).

CONCLUSIONS

High-intensity smoking cessation interventions in hospital settings can be effective for smoking cessation in smokers with high nicotine dependence. In addition, the results suggest that for quitters to maintain long-term abstinence, they should receive regular follow-up counseling for 1 year after completing a high-intensity smoking cessation intervention.

摘要

目的

本研究旨在确定参加住院治疗计划的吸烟者的复发模式,并调查与复发相关的因素。

方法

参与者包括 2015 年至 2018 年期间参加大田烟草控制中心住院治疗的 463 名吸烟者。参与者接受了为期 5 天的高强度戒烟干预,包括药物治疗和行为支持,并在出院后继续进行为期 1 年的随访,以确定他们是否在出院后继续戒烟。采用 Kaplan-Meier 和 Cox 比例风险模型进行分析。

结果

参与者在 1 年内的复发率为 72.8%,59.8%的参与者在参与后 6 个月内再次吸烟。接受更多的咨询次数与复发风险降低显著相关(风险比[HR],0.23;95%置信区间[CI],0.17 至 0.32,≥9 次 vs. ≤5 次)。相反,使用尼古丁替代疗法(NRT)(HR,1.91;95%CI,1.43 至 2.55,使用 vs. 不使用)和较高的基线呼出一氧化碳(CO)水平(HR,1.58;95%CI,1.21 至 2.06,呼出 CO 浓度为 10-19 ppm 与呼出 CO 浓度<10 ppm 相比)与较高的复发率显著相关。

结论

在医院环境中进行高强度戒烟干预对于高尼古丁依赖的吸烟者戒烟可能是有效的。此外,研究结果表明,为了使戒烟者保持长期戒烟,他们应该在完成高强度戒烟干预后接受为期 1 年的定期随访咨询。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58c5/8298987/cdf7f7c59991/epih-43-e2021043f1.jpg

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