Department of Family Medicine, Mackay Memorial Hospital, Taipei 106, Taiwan.
Department of Family Medicine, Taipei Municipal Wanfang Hospital, Taipei Medical University, Taipei 116, Taiwan.
Int J Environ Res Public Health. 2019 Sep 18;16(18):3462. doi: 10.3390/ijerph16183462.
Smoking cessation in the elderly is very important. This study aims to explore the success rate of smoking cessation in the elderly and the factors that predict the success of smoking cessation. We collected data from smokers ≥60 years who visited a medical center in Taiwan during 2017. All patients were prescribed either varenicline or nicotine replacement therapy (NRT) for smoking cessation. The participants were asked about their smoking status after treatment. In total, 129 participants were enrolled. The three- or six-month point abstinence rate was 48.1%. No significant difference was found among baseline characteristics (including age, gender, underlying diseases, smoking duration, daily consumption amount of cigarette, carbon monoxide concentration, Fagerström test for nicotine dependence scores, and treatment method) between quitters and non-quitters, except for the type of medication used. The proportion of quitters using varenicline was significantly higher than that of non-quitters. Multivariate regression analyses showed that the patients who received varenicline were 3.22 times more likely to quit smoking than those who received NRT. Therefore, we suggest that varenicline use may help in smoking cessation in older adults, compared to NRT. Other baseline characteristics may not affect the success rate of smoking cessation in this population.
老年人戒烟非常重要。本研究旨在探讨老年人戒烟的成功率以及预测戒烟成功的因素。我们收集了 2017 年在台湾一家医疗中心就诊的≥60 岁吸烟者的数据。所有患者均接受了伐尼克兰或尼古丁替代疗法（NRT）戒烟治疗。治疗后询问患者的吸烟状况。共纳入 129 名参与者。3 个月或 6 个月的戒烟率为 48.1%。在戒烟者和非戒烟者之间，除了使用的药物类型外，基线特征（包括年龄、性别、基础疾病、吸烟时间、每日吸烟量、一氧化碳浓度、尼古丁依赖 Fagerström 测试评分和治疗方法）无显著差异。使用伐尼克兰的戒烟者比例明显高于非戒烟者。多变量回归分析显示，接受伐尼克兰治疗的患者戒烟的可能性是接受 NRT 治疗的患者的 3.22 倍。因此，与 NRT 相比，我们建议伐尼克兰的使用可能有助于老年人戒烟。其他基线特征可能不会影响该人群的戒烟成功率。
