Division of Infectious Disease, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas, USA.
Cusco Branch-Tropical Medicine Institute, Universidad Peruana Cayetano Heredia, Cusco, Peru.
Vector Borne Zoonotic Dis. 2021 Sep;21(9):707-712. doi: 10.1089/vbz.2020.2753. Epub 2021 Jun 14.
Fascioliasis is a zoonotic infection linked to significant economic losses in the livestock industry. Infection prevalence and estimated financial burden vary across locations owing to different diagnostic tests used. The accuracy of liver condemnation to estimate the prevalence and costs of fascioliasis has seldom been evaluated. We performed a pilot study to determine the prevalence and burden of infection among cattle slaughtered at the municipal abattoir in the Anta province of the Cusco highlands in Peru. We compared liver condemnation with bile microscopy for the diagnosis of infection and prediction of carcass weight. Data were collected from 2009 slaughtered cattle for 1 year. The overall prevalence of infection by bile microscopy was 62.5% (1247/2009). A higher prevalence was observed after the rainy season from March to August than from September to February ( < 0.01). Fascioliasis prevalence during the first 6 months was 77.4% (714/923), combining the results of condemnation and microscopy. Bile microscopy diagnosed more infections than liver condemnation (62.7% (579/923) versus 55.4% (511/923), McNemar test < 0.01). The agreement of the bile microscopy testing with liver condemnation was fair ( = 0.247). Animal age, gender, breed, and liver condemnation predicted carcass weight [F ( 4, 704) = 61.1, < 0.001]. Liver condemnation and bile microscopy are complementary tools for evaluation of the prevalence and burden of fascioliasis in livestock. Large scale studies are warranted to confirm our results.
片形吸虫病是一种人畜共患的感染，给畜牧业带来了重大的经济损失。由于使用了不同的诊断检测方法，感染的流行率和估计的经济负担在不同地区有所不同。肝废弃率评估片形吸虫病的流行率和成本的准确性很少得到评估。我们进行了一项试点研究，以确定秘鲁库斯科高地安塔省市屠宰场屠宰的牛感染的流行率和负担。我们比较了肝废弃率与胆汁显微镜检查，以诊断感染和预测胴体重量。从 2009 年屠宰的牛中收集了为期 1 年的数据。通过胆汁显微镜检查，感染的总体流行率为 62.5%（1247/2009）。从 3 月到 8 月的雨季后，观察到更高的流行率，而不是从 9 月到 2 月（ < 0.01）。在头 6 个月，将肝废弃和显微镜检查的结果结合起来，感染的流行率为 77.4%（714/923）。胆汁显微镜检查诊断出的感染比肝废弃率多（62.7%（579/923）比 55.4%（511/923），McNemar 检验 < 0.01）。胆汁显微镜检查与肝废弃率的一致性为中等（ = 0.247）。动物年龄、性别、品种和肝废弃率预测胴体重量[F ( 4, 704) = 61.1， < 0.001]。肝废弃和胆汁显微镜检查是评估家畜片形吸虫病流行率和负担的互补工具。需要进行大规模研究来证实我们的结果。
