CINTESIS, Faculty of Medicine of University of Porto, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.
3B's Research Group, I3Bs-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence On Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência E Tecnologia, Zona Industrial da Gandra, 4805-017, Barco, Guimarães, Portugal.
Sci Rep. 2021 Jun 16;11(1):12659. doi: 10.1038/s41598-021-92175-2.
This study aimed to compare the efficacy of XP-endo Finisher R and IrriSafe, with a solvent mixture of Methyl ethyl ketone/Tetrachloroethylene (MEK/TCE), in the removal of root filling residues. Twenty-four human mandibular incisors were pair-matched by micro-computed tomography according to volume and aspect ratio. After retreatment, specimens were allocated to two experimental groups (n = 12), according to the supplementary instrument used. The volume of residual filling material after each irrigating step and the time for retreatment was calculated. Statistical analyses were carried out using Mann-Whitney test, with a significance level of 5%. The volume of initial root canal filling material between the groups was similar (p > 0.05). With the final irrigation protocol (NaOCl and EDTA) the volume of the filling remnants decreased significantly (p < 0.05) with no differences between IrriSafe or XP-endo Finisher R (p > 0.05). The additional solvent mixture MEK/TCE increased the efficiency of filling materials reduction, regardless of the agitating instruments employed, IrriSafe or XP-endo Finisher R (p < 0.05). There was no difference between the two groups regarding the time (p = 0.149). Both supplementary instruments were effective in the reduction of filling remnants. The additional step with a solvent mixture of MEK/TCE enabled a total recovery of patency and the achievement of cleaner canals, independently of the agitation instrument.
本研究旨在比较 XP-endo Finisher R 和 IrriSafe 与混合溶剂(甲乙酮/四氯乙烯,MEK/TCE)在去除根管充填残留物方面的疗效。根据体积和长宽比,通过微计算机断层扫描将 24 个人类下颌切牙配对。再治疗后,根据使用的附加仪器将标本分为两组(n=12)。计算每个冲洗步骤后的残留填充材料体积和再治疗时间。使用曼-惠特尼检验进行统计学分析,显著性水平为 5%。两组间初始根管内充填材料的体积相似(p>0.05)。采用最终冲洗方案(次氯酸钠和 EDTA)后,填充物残余物的体积明显减少(p<0.05),但 IrriSafe 或 XP-endo Finisher R 之间无差异(p>0.05)。无论使用的搅拌仪器是 IrriSafe 还是 XP-endo Finisher R,添加 MEK/TCE 溶剂混合物都能提高填充物减少的效率(p<0.05)。两组之间的时间没有差异(p=0.149)。两种附加仪器都能有效减少填充物残余物。添加 MEK/TCE 溶剂混合物的额外步骤可以实现完全通畅和更清洁的根管,而与搅拌仪器无关。