A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Russian Academy of Sciences, ul. Palchevskogo 17, Vladivostok, 690041, Russia.
Arch Microbiol. 2021 Sep;203(7):4461-4473. doi: 10.1007/s00203-021-02432-1. Epub 2021 Jun 17.
A cultivated form of bacteria (strain 2202) was isolated from the hemal fluid of the bivalve mollusk Modiolus kurilensis. Based on the set of data collected by genetic and physiological/biochemical analyses, the strain was identified as the species Pseudoalteromonas piscicida. Strain 2202 exhibits antimicrobial activity against Staphylococcus aureus, Candida albicans, and Bacillus subtilis but not against Escherichia coli and Pseudomonas aeruginosa. These activities characterize the behavior of strain 2202 as predator-like and classify it as a facultative predator. Being part of the normal microflora in the hemolymph of M. kurilensis, when external conditions change, strain 2202 shows features of opportunistic microflora. The strain 2202 exhibits selective toxicity towards larvae of various invertebrates: it impairs the early development of Mytilus edulis, but not of Strongylocentrotus nudus. Thus, the selective manner in which P. piscicida strains interact with various species of microorganisms and eukaryotes should be taken into consideration when using their biotechnological potential as a probiotic in aquaculture, source of antimicrobial substances, and factors that prevent fouling.
从双壳贝类贻贝（Modiolus kurilensis）的血液中分离出一种经过培养的细菌（菌株 2202）。基于遗传和生理/生化分析收集的数据，该菌株被鉴定为假交替单胞菌（Pseudoalteromonas piscicida）。菌株 2202 对金黄色葡萄球菌、白色念珠菌和枯草芽孢杆菌具有抗菌活性，但对大肠杆菌和铜绿假单胞菌没有活性。这些活性表明菌株 2202 的行为类似于捕食者，并将其归类为兼性捕食者。作为贻贝血液中正常微生物群的一部分，当外部条件发生变化时，菌株 2202 表现出机会性微生物群的特征。该菌株 2202 对各种无脊椎动物幼虫表现出选择性毒性：它会损害贻贝的早期发育，但不会损害海参的早期发育。因此，在利用其作为水产养殖中的益生菌、抗菌物质的来源以及防止污垢的因素的生物技术潜力时，应考虑假交替单胞菌菌株与各种微生物和真核生物相互作用的选择性方式。
