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D2A U-Net:基于双重注意力和混合空洞卷积的 COVID-19 CT 切片自动分割。

D2A U-Net: Automatic segmentation of COVID-19 CT slices based on dual attention and hybrid dilated convolution.

机构信息

School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China.

School of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China; Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100191, China.

出版信息

Comput Biol Med. 2021 Aug;135:104526. doi: 10.1016/j.compbiomed.2021.104526. Epub 2021 Jun 2.

Abstract

Coronavirus Disease 2019 (COVID-19) has become one of the most urgent public health events worldwide due to its high infectivity and mortality. Computed tomography (CT) is a significant screening tool for COVID-19 infection, and automatic segmentation of lung infection in COVID-19 CT images can assist diagnosis and health care of patients. However, accurate and automatic segmentation of COVID-19 lung infections is faced with a few challenges, including blurred edges of infection and relatively low sensitivity. To address the issues above, a novel dilated dual attention U-Net based on the dual attention strategy and hybrid dilated convolutions, namely D2A U-Net, is proposed for COVID-19 lesion segmentation in CT slices. In our D2A U-Net, the dual attention strategy composed of two attention modules is utilized to refine feature maps and reduce the semantic gap between different levels of feature maps. Moreover, the hybrid dilated convolutions are introduced to the model decoder to achieve larger receptive fields, which refines the decoding process. The proposed method is evaluated on an open-source dataset and achieves a Dice score of 0.7298 and recall score of 0.7071, which outperforms the popular cutting-edge methods in the semantic segmentation. The proposed network is expected to be a potential AI-based approach used for the diagnosis and prognosis of COVID-19 patients.

摘要

新型冠状病毒病(COVID-19)由于其高传染性和高死亡率,已成为全球最紧迫的公共卫生事件之一。计算机断层扫描(CT)是 COVID-19 感染的重要筛查工具,对 COVID-19 CT 图像中肺部感染的自动分割可以辅助诊断和治疗患者。然而,COVID-19 肺部感染的准确和自动分割面临着一些挑战,包括感染边界模糊和相对较低的灵敏度。为了解决上述问题,提出了一种基于双注意力策略和混合扩张卷积的新型扩张双注意力 U-Net(D2A U-Net),用于 COVID-19 CT 切片中的病变分割。在我们的 D2A U-Net 中,利用由两个注意力模块组成的双注意力策略来细化特征图并减少不同层次特征图之间的语义差距。此外,混合扩张卷积被引入到模型解码器中,以实现更大的感受野,从而细化解码过程。该方法在一个开源数据集上进行了评估,Dice 得分为 0.7298,召回率得分为 0.7071,优于语义分割领域的流行前沿方法。该网络有望成为一种基于人工智能的 COVID-19 患者诊断和预后的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/385d/8169238/124904128691/gr1_lrg.jpg

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