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延迟性胰瘘:胰十二指肠切除术后一种不常见的并发症——一例罕见病例报告

Delayed pancreatic fistula: An unaccustomed complication following pancreaticoduodenectomy- a rare case report.

作者信息

Jena Suvendu Sekhar, Meher Dibyasingh, Ranjan Rahul

机构信息

Department of Surgical Gastroenterology and Liver Transplantation, Sir Ganga Ram Hospital, New Delhi, 110060, India.

Department of General Surgery, VMMC and Safdarjung Hospital, New Delhi, India.

出版信息

Ann Med Surg (Lond). 2021 Jun 7;66:102460. doi: 10.1016/j.amsu.2021.102460. eCollection 2021 Jun.

Abstract

INTRODUCTION

and Importance: Post-operative pancreatic fistula is a morbid complication after pancreaticoduodenectomy. Though most of them present in the immediate post-operative period, few case reports have mentioned it even 7 years after index surgery. Here, we report a delayed presentation of pancreatic fistula 6 months after surgery.

CASE PRESENTATION

A 57 year old female underwent Whipple's pancreaticoduodenectomy for pancreatic head adenocarcinoma and was discharged with an uneventful post-operative recovery. She presented after 6 months with complaints of abdominal pain and distension which upon evaluation was found to be a pancreatic enzyme rich mutiloculated collection. It was managed with per-cutaneous drain placement.

CLINICAL DISCUSSION

Pancreatic fistula remained a major cause of morbidity and mortality even after 100 years of its existence. It can be overt fistula which manifest in the immediate post-operative period or occult fistula which manifests long after primary surgery. Various causes of delayed fistula are anastomotic site stricture, previous chemotherapy, infection. The management options available are percutaneous drainage, endoscopic stenting of anastomotic stricture or redoing the anastomosis.

CONCLUSION

Pancreatic fistula can have a delayed presentation which can be diagnosed and managed with regular follow up

摘要

引言

及重要性:术后胰瘘是胰十二指肠切除术后的一种严重并发症。尽管大多数胰瘘在术后即刻出现,但很少有病例报告提及在初次手术7年后仍有发生。在此,我们报告一例术后6个月出现的延迟性胰瘘病例。

病例介绍

一名57岁女性因胰头腺癌接受了惠普尔胰十二指肠切除术,术后恢复顺利并出院。6个月后,她因腹痛和腹胀前来就诊,经评估发现是一个富含胰酶的多房性积液。通过经皮置管引流进行处理。

临床讨论

即使在胰瘘存在100年后,它仍然是发病率和死亡率的主要原因。它可以是在术后即刻出现的明显瘘,也可以是在初次手术后很久才出现的隐匿性瘘。延迟性瘘的各种原因包括吻合口狭窄、先前的化疗、感染。可用的治疗选择包括经皮引流、吻合口狭窄的内镜支架置入或重新进行吻合。

结论

胰瘘可能会有延迟表现,通过定期随访可以进行诊断和处理

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/289d/8193112/8cd5b07adf28/gr1.jpg

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