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同步性转移至胆囊的透明细胞肾细胞癌伴异时性对侧复发

Synchronous Metastatic Clear Cell Renal Cell Carcinoma to the Gallbladder With Metachronous Contralateral Recurrence.

作者信息

Pierce Daniel P, Dahmen Aaron S, Hernandez David J

机构信息

Department of Urology, University of South Florida, Tampa, USA.

出版信息

Cureus. 2021 May 13;13(5):e15007. doi: 10.7759/cureus.15007.

Abstract

Renal cell carcinoma (RCC) classically metastasizes to the lungs, bones, adrenals, lymph nodes, liver, and brain. RCC metastasis to the gallbladder is rare occurring in less than 1% of metastases. We present a case of a 60-year-old male who at initial diagnosis of his large left renal mass was incidentally found to have a gallbladder mass. He underwent simultaneous open radical nephrectomy and cholecystectomy with pathology confirming solitary metastatic clear cell RCC (ccRCC). The patient chose surveillance and was without evidence of disease for three years. At three years, imaging showed a 2 cm contralateral renal mass which was cryoablated percutaneously. This case demonstrates not only the importance of a thorough review of initial and surveillance imaging but also of maintaining a broad differential for other solid organ masses in the setting of a primary RCC of the kidney.

摘要

肾细胞癌(RCC)通常转移至肺、骨、肾上腺、淋巴结、肝脏和脑。RCC转移至胆囊罕见,发生率低于转移病例的1%。我们报告一例60岁男性,在初诊发现左肾巨大肿块时偶然发现胆囊有肿块。他同时接受了开放性根治性肾切除术和胆囊切除术,病理证实为孤立性转移性透明细胞肾细胞癌(ccRCC)。患者选择了观察,三年来无疾病证据。三年时,影像学检查显示对侧肾脏有一个2 cm的肿块,经皮进行了冷冻消融。该病例不仅证明了全面复查初始和监测影像学的重要性,也证明了在原发性肾RCC情况下,对其他实体器官肿块保持广泛鉴别诊断的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/15d9/8202448/5e1c6318ce55/cureus-0013-00000015007-i01.jpg

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