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[与功能保留相兼容的直肠癌治疗方法]

[Rectal cancer therapy compatible with preservation of function].

作者信息

Yasutomi M, Shindo K, Matsuda T, Maruyama J, Morikawa E, Kubo R, Hida J

机构信息

Dept. of Surgery, Kinki University, School of Medicine.

出版信息

Gan To Kagaku Ryoho. 1988 Sep;15(9):2681-5.

PMID:3415265
Abstract

Rectal cancer surgery causes often postoperative morbidities such as defecation disturbance, dysuria and male sexual impotence. Compatibility of cancer eradication and function preservation are the problem should be resolved in the rectal cancer surgery. Defecation function were preserved in the patients with middle and upper rectal cancer by anterior resection transsacral resection, invagination or pull-through operation. Since 1984, usage of suture instruments made it practicable to increase sphincter preserving operation up to more than 65% of rectal cancer. Postoperative 5-years survivals were 81% of anterior resection, 71% of invagination operation and 57% of pull-through. Autonomic nerves preserving operation (ANP), aimed to prevent the urinary and sexual disfunction were studied both sides of the cancer spreads and extend of nerve plexuses. And ANP were adopted to the 185 cancers, limited to the submucosa or the proper muscle coat, by Study Group of Welfare Ministry. Their postoperative disfunction decreased to 15% of urination and 21% of male potency, while 33% and 81% respectively following conventional operation. Local excision for early cancer, which are defined as mucosal or submucosal cancer are discussed.

摘要

直肠癌手术常常会导致术后出现诸如排便障碍、排尿困难和男性性功能障碍等并发症。根治癌症与保留功能的兼容性是直肠癌手术中需要解决的问题。通过经骶前切除术、内翻术或拖出术,中高位直肠癌患者的排便功能得以保留。自1984年以来,缝合器械的使用使得保肛手术的比例提高到了直肠癌手术的65%以上。前切除术的术后5年生存率为81%,内翻术为71%,拖出术为57%。旨在预防泌尿和性功能障碍的保留自主神经手术(ANP),针对癌症扩散和神经丛延伸的两侧进行了研究。福利部研究小组对185例局限于黏膜下层或固有肌层的癌症采用了ANP。其术后功能障碍分别降至排尿功能障碍的15%和男性性功能障碍的21%,而传统手术分别为33%和81%。本文还讨论了早期癌症(定义为黏膜或黏膜下癌)的局部切除术。

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