Department of Ophthalmology, Elazığ City Hospital, Elazığ, Turkey.
Bosn J Basic Med Sci. 2021 Dec 1;21(6):782-786. doi: 10.17305/bjbms.2021.5840.
The aim of this study was to evaluate the effects of COVID-19 on central foveal and choroidal thicknesses. Thirty-two patients with a positive SARS-CoV-2 PCR test who received outpatient treatment within the previous two months and 32 healthy controls were included in the study. Patients requiring hospitalization due to COVID-19 as well as the patients who received either intensive care support and/or antiplatelet therapy, smokers, or patients with systemic or ocular diseases were excluded from the study. After full ophthalmological examination, central foveal and choroidal thicknesses were evaluated by using optical coherence tomography. Statistical analysis of the study data demonstrated no significant difference between the groups in terms of age or gender (p>0.05). There was also no statistically significant difference between the groups in terms of central foveal thickness, central choroidal thickness, or nasal 500, nasal 1500, temporal 500, or temporal 500-micron distances (p>0.05 for all parameters). Choroidal and retinal thicknesses were not affected in patients with recent mild COVID 19 without comorbidities.
本研究旨在评估 COVID-19 对中央凹和脉络膜厚度的影响。研究纳入了 32 名在过去两个月内接受门诊治疗且 SARS-CoV-2 PCR 检测呈阳性的患者和 32 名健康对照者。因 COVID-19 需要住院治疗以及接受重症监护支持和/或抗血小板治疗、吸烟者或患有系统性或眼部疾病的患者被排除在研究之外。在进行全面的眼科检查后，使用光学相干断层扫描评估中央凹和脉络膜厚度。对研究数据的统计学分析显示，两组在年龄或性别方面无显著差异（p＞0.05）。两组在中央凹厚度、脉络膜中央厚度或鼻侧 500、鼻侧 1500、颞侧 500 或颞侧 500 微米距离方面也无统计学差异（所有参数 p＞0.05）。无合并症的近期轻度 COVID-19 患者的脉络膜和视网膜厚度不受影响。
