Husslein H, Breitenecker G, Tatra G
Acta Obstet Gynecol Scand. 1978;57(1):73-8. doi: 10.3109/00016347809154202.
29 female immunosuppressed renal transplant recipients were examined gynecologically. In 2 cases the epithelium of the portio was found to be dysplastic, while endometrial carcinoma was present in 1 patient. A review of the literature suggests that immunosuppressed patients are more likely to develop tumors than others. The authors stress the need for gynecological and cytological examinations at short intervals, to identify premalignant and early malignant uterine changes at a time at which these can readily be treated without discontinuation of the immunosuppressive therapy.
对29名接受免疫抑制治疗的女性肾移植受者进行了妇科检查。发现2例宫颈上皮发育异常，1例患有子宫内膜癌。文献回顾表明，免疫抑制患者比其他人更容易发生肿瘤。作者强调需要每隔一段时间进行妇科和细胞学检查，以便在子宫发生癌前和早期恶性病变时能够及时发现，此时这些病变可以在不中断免疫抑制治疗的情况下得到有效治疗。
