Friends Research Institute, Inc., 6910 Santa Monica Boulevard, Los Angeles, CA, 90038, USA.
Department of Family Medicine, Center for HIV Identification, Prevention and Treatment Services, University of California, Los Angeles, CA, USA.
AIDS Behav. 2021 Sep;25(9):3011-3023. doi: 10.1007/s10461-021-03352-3. Epub 2021 Jun 24.
Young adult trans women living with HIV in the US exhibit suboptimal advancement through the HIV Care Continuum relative to national averages. From December 2016 through May 2018, 134 young adult trans women living with HIV enrolled in Text Me, Girl!, a theory-based, trans-specific text-messaging intervention designed to improve HIV Care Continuum outcomes. Participants (N = 130) averaged 29.5 years, were predominantly Latinx (43%) or African American/Black (40%). Clustered logistic and ordinal logistic multivariable models (n = 105; 366 observations) indicate that through 18-month follow-up, increased exposure to the text-messaging intervention was associated with significant (p < 0.05) increased retention to HIV care (adjusted odds ratio [aOR] 1.33) and biomarker-confirmed viral suppression (aOR 1.51); retention in the intervention was associated with significantly increased likelihood of ART uptake (aOR 2.95) and "excellent" ART adherence (aOR 10.44). Text Me, Girl! offers promising evidence that a unidirectional, automated text-messaging intervention can improve HIV care outcomes among young adult trans women living with HIV.
美国的年轻成年跨性别女性艾滋病毒感染者在艾滋病毒护理连续体中的进展情况逊于全国平均水平。2016 年 12 月至 2018 年 5 月，134 名生活在艾滋病毒中的年轻成年跨性别女性参加了 Text Me，Girl！，这是一项基于理论的、专门针对跨性别者的短信干预措施，旨在改善艾滋病毒护理连续体的结果。参与者（N=130）平均年龄为 29.5 岁，主要是拉丁裔（43%）或非裔美国人/黑人（40%）。聚类逻辑和有序逻辑多变量模型（n=105；366 次观察）表明，在 18 个月的随访中，更多地接触短信干预与艾滋病毒护理（调整优势比[aOR]1.33）和生物标志物确认的病毒抑制（aOR 1.51）的保留显著相关；保留在干预措施中与接受抗逆转录病毒治疗（ART）的可能性显著增加（aOR 2.95）和“优秀”的 ART 依从性（aOR 10.44）相关。Text Me，Girl！提供了有希望的证据，表明单向、自动化的短信干预可以改善生活在艾滋病毒中的年轻成年跨性别女性的艾滋病毒护理结果。
