Hermann B P, Wyler A R, Steenman H, Richey E T
Regional Epilepsy Center, Baptist Memorial Hospital, Memphis, Tennessee.
Cortex. 1988 Jun;24(2):245-53. doi: 10.1016/s0010-9452(88)80033-9.
The purpose of this investigation was to inquire into the relationship between demographic, seizure related, and language factors with the adequacy of verbal learning and memory function in 25 patients with complex partial seizures of dominant temporal lobe origin. Language function in general, and measures of verbal comprehension (aural and reading) and retrieval ability (naming and associative fluency) in particular, emerged as the most robust predictors of verbal learning and memory performance in this sample. Our findings both supported and extended the hypothesis of Mayeux et al. (1980) of a relationship between adequacy of language function and verbal learning and memory performance in patients with complex partial seizures. The implications of these findings for studies investigating the relationship between complex partial seizures/temporal lobe pathology and memory function are discussed.
本研究的目的是探究25例起源于优势颞叶的复杂部分性癫痫患者的人口统计学、癫痫相关因素和语言因素与言语学习及记忆功能充分性之间的关系。总体而言，语言功能，尤其是言语理解（听觉和阅读）及提取能力（命名和联想流畅性）的测量指标，是该样本中言语学习和记忆表现的最有力预测因素。我们的研究结果既支持又扩展了Mayeux等人（1980年）提出的关于复杂部分性癫痫患者语言功能充分性与言语学习和记忆表现之间关系的假说。本文讨论了这些发现对研究复杂部分性癫痫/颞叶病变与记忆功能之间关系的意义。
