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经桡动脉入路行冠状动脉介入治疗的学习曲线。

The learning curve of the distal radial access for coronary intervention.

机构信息

Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine and Cardiovascular Center, Yongin Severance Hospital, 363 Dongbaekjukjeon-daero, Giheung-gu, Yongin, 16995, Republic of Korea.

Department of Cardiology, Chonnam National University Hospital, Gwangju, Republic of Korea.

出版信息

Sci Rep. 2021 Jun 24;11(1):13217. doi: 10.1038/s41598-021-92742-7.

Abstract

Recently, coronary angiography (CAG) and percutaneous coronary intervention (PCI) via the distal radial access (DRA), are gaining attention owing to fewer complications. Despite the advantages of the DRA, there is difficulty to initiate this new vascular approach. The data from 1000 patients who underwent CAG and PCI via the DRA by a single experienced radial operator were retrospectively analyzed. The primary outcome was the success rate of the DRA per 100 cases. Moreover, the predictors of the failed DRA were analyzed. Overall, 952 (95.2%) of the total 1,000 patients underwent a successful DRA. After experiencing 200 cases, the DRA success rate was well maintained at > 94%, and there was no difference in success rate per 100 cases (P = 0.216). The predictors of failure were female sex [odds ratio (OR) 1.84, 95% confidence interval (CI) 1.01-3.39, P = 0.049] and systolic blood pressure (SBP) of < 120 mmHg (OR 1.87, 95% CI 1.04-3.36, P = 0.036). For achieving a stable DRA with the success rate of > 94%, 200 procedures would be needed. Moreover, this new approach could fail in women and patients with low SBP.Trial registration: https://cris.nih.go.kr/cris/index/index.do (Unique identifier: KCT0005349).

摘要

最近,由于并发症较少,经远端桡动脉入路(DRA)的冠状动脉造影(CAG)和经皮冠状动脉介入治疗(PCI)受到关注。尽管 DRA 具有优势,但启动这种新的血管入路仍存在困难。回顾性分析了由一位经验丰富的桡动脉操作者对 1000 例接受 DRA 行 CAG 和 PCI 的患者的数据。主要结局为每 100 例 DRA 的成功率。此外,还分析了 DRA 失败的预测因素。总体而言,1000 例患者中有 952 例(95.2%)成功进行了 DRA。在经历了 200 例病例后,DRA 的成功率很好地维持在>94%,每 100 例的成功率没有差异(P=0.216)。失败的预测因素是女性(比值比 [OR] 1.84,95%置信区间 [CI] 1.01-3.39,P=0.049)和收缩压(SBP)<120mmHg(OR 1.87,95%CI 1.04-3.36,P=0.036)。为了实现成功率>94%的稳定 DRA,需要进行 200 例手术。此外,这种新方法可能会在女性和 SBP 较低的患者中失败。试验注册:https://cris.nih.go.kr/cris/index/index.do(唯一标识符:KCT0005349)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/531a/8225842/1b58a63a4881/41598_2021_92742_Fig1_HTML.jpg

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