Dermatological Clinic Department of Clinical and Molecular Sciences, Marche Polytechnic University, Ancona, Italy.
Hum Vaccin Immunother. 2021 Oct 3;17(10):3268-3275. doi: 10.1080/21645515.2021.1925502. Epub 2021 Jun 25.
Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects approximately 20% of children and 10% of adults. The implication of vaccines as a trigger for the de novo onset of AD in children or as a cause of exacerbation in individuals with a history of AD has long been debated. We present a brief review of the literature on AD and traditional vaccinations, proposing in addition the main recommendations for the management of patients with AD undergoing the vaccine against the SARS-COV-2 virus. Live attenuated vaccines seem to be associated with a relapse of AD and/or complications, such as eczema vaccinatum. For non-live vaccines, no adverse events are noted in atopic subjects. Since the Covid-19 vaccine is mRNA or viral vectored vaccine and there are no other currently used vaccines of this type, the same recommendations are applied as for all other non-live vaccines.
特应性皮炎(AD)是一种慢性炎症性皮肤病,影响约 20%的儿童和 10%的成年人。疫苗作为儿童新发 AD 的触发因素,或作为有 AD 病史者病情恶化的原因,长期以来一直存在争议。我们简要回顾了 AD 和传统疫苗接种的文献,此外还提出了接受 SARS-COV-2 病毒疫苗的 AD 患者管理的主要建议。减毒活疫苗似乎与 AD 复发和/或并发症(如疫苗引起的牛痘疹)有关。对于非活疫苗,在特应性受试者中未观察到不良事件。由于新冠病毒疫苗是 mRNA 或病毒载体疫苗,而目前没有其他类型的此类疫苗,因此与所有其他非活疫苗一样,也适用相同的建议。