Department of Urology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania;
Rom J Morphol Embryol. 2020 Oct-Dec;61(4):1227-1233. doi: 10.47162/RJME.61.4.24.
The incidence of nephrolithiasis is in full expansion, its etiology being frequently associated with lifestyle changes. The objective of this retrospective study, carried out between April and December 2019, was to identify the correlations of the known lithogenic factors with the chemical structure of the calculi in the patients from the North-Eastern region of Romania. The results obtained after the data analysis of our LAMPA questionnaire (L - liquids, A - antecedents, M - medication, P - associated pathologies, A - aliments) made in evidence a statistically relevant relationship between the heredocollateral history of lithiasis and calcium oxalate dihydrate (COD) calculi, hypertension and calcium oxalate monohydrate (COM) stones, uric lithiasis and diabetes, COD, and obesity, between predominantly uric lithiasis and meat or meat-derived products consumption, between frequent potato consumption and COD stones and the frequently consume of dairy products and predominantly COM calculi. The authors concluded that the use of a complex questionnaire, like LAMPA, together with Fourier-transform infrared (FTIR) spectroscopic and morphological analysis are essential steps for developing an efficient metaphylaxis.
肾结石的发病率正在全面扩张,其病因常与生活方式的改变有关。本回顾性研究于 2019 年 4 月至 12 月进行,旨在确定已知结石形成因素与罗马尼亚东北部患者结石化学结构之间的相关性。通过对我们的 LAMPA 问卷(L - 液体,A - 病史,M - 药物,P - 相关疾病,A - 饮食)进行数据分析后,结果表明结石的遗传性疾病与草酸钙二水合物(COD)结石、高血压和草酸钙一水合物(COM)结石之间存在统计学上显著的关系,尿酸结石与糖尿病有关,与肥胖有关,主要为尿酸结石与肉类或肉类产品消费有关,经常食用土豆与 COD 结石有关,经常食用乳制品与主要为 COM 结石有关。作者得出结论,使用复杂的问卷(如 LAMPA)结合傅里叶变换红外(FTIR)光谱和形态分析是制定有效预防措施的重要步骤。