久坐时间、体力活动和体质与中年久坐成年人 1,25-二羟维生素 D 的关系：FIT-AGEING 研究。
Relationship of sedentary time, physical activity and fitness with 1,25-dihydroxyvitamin D in middle-aged sedentary adults: The FIT-AGEING study.
机构信息
EFFECTS-262 Research Group, Department of Physiology, Faculty of Medicine, University of Granada, 18071 Granada, Spain.
EFFECTS-262 Research Group, Department of Physiology, Faculty of Medicine, University of Granada, 18071 Granada, Spain; PROmoting FITness and Health Through Physical Activity (PROFITH) Research Group, Sport and Health University Research Institute, Department of Physical Education and Sports, Faculty of Sport Sciences, University of Granada, 18071 Granada, Spain.
出版信息
Exp Gerontol. 2021 Sep;152:111458. doi: 10.1016/j.exger.2021.111458. Epub 2021 Jun 22.
PURPOSE
Potential interactions between sedentary behaviour, physical activity (PA), and physical fitness with 25-hydroxyvitamin D (25(OH)D) status have been previously suggested. However, data are scarce concerning the association between these predictors of general health and the main active metabolite of vitamin D, the 1,25-dihidroxyvitamin D (1,25(OH)D). This study aimed to analyse the relationship of sedentary time, PA levels, and physical fitness (i.e., maximal oxygen uptake (VOmax) and muscular strength) with 1,25(OH)D in middle-aged sedentary adults.
METHODS
A total of 73 (39 women) middle-aged sedentary adults (53.7 ± 5.1 years old) participated in this cross-sectional study. Sedentary time and PA intensity levels were objectively measured with triaxial accelerometers for 7 consecutive days. VOmax was determined by a maximum treadmill test. Lower and upper limb muscular strength was assessed by an isokinetic strength test and by a handgrip strength test, respectively. 1,25(OH)D plasma levels were measured using a DiaSorin Liaison® immunochemiluminometric assay.
RESULTS
No significant relationships were found between objectively measured sedentary time, PA levels or physical fitness (i.e., VOmax, extension and flexion peak torque, and hand grip strength) and 1,25(OH)D (all P > 0.05). All results persisted after controlling for age, sex, fat mass or energy, vitamin D, calcium, and phosphorus intake.
CONCLUSIONS
In summary, our results show that vitamin D status is not affected by physical activity habits and sedentary behaviour in middle-aged sedentary adults.
目的
久坐行为、体力活动（PA）和身体健康的预测因素与 25-羟维生素 D（25（OH）D）状态之间的潜在相互作用此前已有报道。然而，关于这些一般健康预测因素与维生素 D 的主要活性代谢物 1,25-二羟维生素 D（1,25（OH）D）之间的关联的数据还很有限。本研究旨在分析久坐时间、PA 水平和身体健康（即最大摄氧量（VOmax）和肌肉力量）与中年久坐成年人的 1,25（OH）D 之间的关系。
方法
共有 73 名（39 名女性）中年久坐成年人（53.7±5.1 岁）参与了这项横断面研究。使用三轴加速度计连续 7 天客观测量久坐时间和 PA 强度水平。VOmax 通过最大跑步机测试确定。下肢和上肢肌肉力量分别通过等速力量测试和握力测试进行评估。使用 DiaSorin Liaison®免疫化学发光分析测定 1,25（OH）D 血浆水平。
结果
未发现客观测量的久坐时间、PA 水平或身体健康（即 VOmax、伸展和屈曲峰值扭矩以及握力）与 1,25（OH）D 之间存在显著关系（所有 P>0.05）。在控制年龄、性别、体脂量或能量、维生素 D、钙和磷摄入后，所有结果仍然存在。
结论
综上所述，我们的结果表明，维生素 D 状态不受中年久坐成年人的体力活动习惯和久坐行为的影响。
Zotero 插件