动脉导管依赖性肺循环姑息治疗中 Blalock-Taussig 分流术与导管支架的比较：系统评价和荟萃分析。
Blalock-Taussig Shunt versus Ductal Stent in the Palliation of Duct Dependent Pulmonary Circulation; A Systematic Review and Metanalysis.
机构信息
Pediatric Cardiology unit, Pediatrics' Department, Faculty of Medicine, Cairo University, Egypt.
Research Accessibility Team, Student and Internship research program Faculty of Medicine, Cairo University, Egypt.
出版信息
Curr Probl Cardiol. 2022 Sep;47(9):100885. doi: 10.1016/j.cpcardiol.2021.100885. Epub 2021 May 8.
In infants with ductal dependent pulmonary blood flow, Blalock-Taussig (BT) shunt and Patent Ductus Arteriosus (PDA) stent, are two palliative procedures aimed to restore circulation. A systematic review and metanalysis was performed on studies comparing PDA stents and BT shunts, in accordance with PRISMA guidelines. Meta-analysis revealed the following; (1) a reduced risk of mortality [RR = 0.585 [0.399-0.859], (P = 0.006)], (2) a reduced risk of complications [RR = 0.523 [0.318-0.860], (P = 0.011), and (3) a reduced risk of ECMO use [R = 0.267 [0.101-0.706] (P = 0.008)], all in the stent group. Additionally, stent group showed higher post procedure oxygen saturation [SMD = 1.307 [95% CI 1.065-1.550], (P < 0.001)], and Nakata index [SMD = 0.679 95% CI [0.513 to 0.845], (P < 0.001)]. PDA stenting presents a viable alternative to BT shunt procedure with better post procedure stability.
在依赖导管的肺血流的婴儿中，Blalock-Taussig（BT）分流术和动脉导管未闭（PDA）支架术是两种旨在恢复循环的姑息性手术。根据 PRISMA 指南，对比较 PDA 支架和 BT 分流术的研究进行了系统评价和荟萃分析。荟萃分析显示：（1）死亡率降低的风险[RR=0.585（0.399-0.859），（P=0.006）]；（2）并发症风险降低的风险[RR=0.523（0.318-0.860），（P=0.011）]；（3）ECMO 使用风险降低的风险[RR=0.267（0.101-0.706），（P=0.008）]，所有这些风险都在支架组中降低。此外，支架组术后氧饱和度更高[SMD=1.307（95%CI 1.065-1.550），（P<0.001）]，Nakata 指数更高[SMD=0.679 95%CI [0.513 至 0.845]，（P<0.001）]。与 BT 分流术相比，PDA 支架术具有更好的术后稳定性，是一种可行的替代方法。
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