Jalili Roghayeh, Irani-Nezhad Mahsa Haddad, Khataee Alireza, Joo Sang Woo
Research Laboratory of Advanced Water and Wastewater Treatment Processes, Department of Applied Chemistry, Faculty of Chemistry, University of Tabriz, 51666-16471 Tabriz, Iran.
Research Laboratory of Advanced Water and Wastewater Treatment Processes, Department of Applied Chemistry, Faculty of Chemistry, University of Tabriz, 51666-16471 Tabriz, Iran; Department of Environmental Engineering, Gebze Technical University, 41400 Gebze, Turkey; Department of Material Science and Physical Chemistry of Materials, South Ural State University, 454080 Chelyabinsk, Russian Federation.
Spectrochim Acta A Mol Biomol Spectrosc. 2021 Dec 5;262:120089. doi: 10.1016/j.saa.2021.120089. Epub 2021 Jun 16.
Herein, we report a ratiometric fluorescent probe based on in situ incorporation of both Gold nanoclusters (AuNCs) and Green emitting carbon dots (gCDs) into zeolitic imidazolate framework-8 (ZIF-8) to analysis of Cephalexin (CFX). Under a single excitation wavelength of 400 nm, the sensor exhibits dual-emissions centered at 520 and 630 nm. The fluorescence of AuNCs (630 nm) is selectively quenched by CFX, whereas the fluorescence of gCDs (520 nm) remainsalmostconstant. The ratiometric fluorescence signal (F/F) of the prepared composite (gCDc/AuNCs @ ZIF-8) is linearly proportional to the concentration of CFX from 0.1 to 6 ng/mL with a low detection limit (LOD) of 0.04 ng/mL, which is below the maximum residues limit (MRL) of 100 ng/mL set by the Food and Drug Administration (FDA). Moreover, the designed sensing platform was successfully applied to detect CFX in the milk samples.
在此，我们报道了一种基于将金纳米簇（AuNCs）和绿色发光碳点（gCDs）原位掺入沸石咪唑酯骨架-8（ZIF-8）中的比率荧光探针，用于头孢氨苄（CFX）的分析。在400nm的单一激发波长下，该传感器呈现出以520nm和630nm为中心的双发射。CFX可选择性猝灭AuNCs（630nm）的荧光，而gCDs（520nm）的荧光几乎保持不变。制备的复合材料（gCDc/AuNCs@ZIF-8）的比率荧光信号（F/F）与CFX浓度在0.1至6ng/mL范围内呈线性比例关系，检测限低至0.04ng/mL，低于美国食品药品监督管理局（FDA）设定的100ng/mL的最大残留限量（MRL）。此外，所设计的传感平台成功应用于牛奶样品中CFX的检测。
