Ahmad Alajlan Saleh, Alhusseini Noara K, Mohammed Basheeruddin Asdaq Syed, Mohzari Yahya, Alamer Ahmad, Alrashed Ahmed A, Alamri Abdulhakeem S, Alsanie Walaa F, Alhomrani Majid
Pediatric Dentistry Department, King Fahad Medical City, Riyadh, Saudi Arabia.
College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Saudi J Biol Sci. 2021 Sep;28(9):4926-4930. doi: 10.1016/j.sjbs.2021.06.047. Epub 2021 Jun 19.
BACKGROUND & OBJECTIVES: In late December 2019, an outbreak of severe acute respiratory syndrome coronavirus 2 (SARS COV-2) occurred in the city of Wuhan, the capital of the Hubei province in the central part of the People's Republic of China (Ren et al., 2020). In Saudi Arabia, the first case of COVID-19 was reported in March 2, 2020. In March 8, 2020, the Saudi authorities adopted the lockdown strategy to contain the disease. The aim of this study was to determine the effectiveness of the various phases of the lockdown strategy in Saudi Arabia and its impact on the basic reproductive number (R0) of the COVID-19 outbreak.
The timeline of the COVID-19 outbreak in Saudi Arabia was divided into three-time intervals. (2020) was used to estimate the changes in community mobility during the various phases of the lockdown. The basic reproductive number (R0) of the COVID-19 outbreak was calculated daily using the Susceptible, Infected and Recovered (SIR) model based on the Saudi Ministry of Health (MOH) daily reports. This is a standard system to determine the spread of the virus on the basis of infection rate, quarantine rate as well as confirmation rate. The mean values of the calculated R0 during each interval were compared using one-way ANOVA test.
There was no statistically significant difference between the mean values of the different phases of the lockdown (P > 0.05). Moreover, mean R0 value of the second interval was 0.09 higher than the initial interval with free community mobility. Furthermore, the mean R0 values of the third interval with the full lockdown was 0.28 higher than the initial interval.
Early implementation of lockdown strategy combined with other social distancing strategies help in containing infectious outbreaks in their early phases. Continuous assessment of such strategies' effectiveness provides decision makers with precious information needed to justify their application when considering their economic impact.
2019年12月下旬,中华人民共和国中部湖北省省会武汉市爆发了严重急性呼吸综合征冠状病毒2(SARS-CoV-2)疫情(任等,2020年)。在沙特阿拉伯,2020年3月2日报告了首例COVID-19病例。2020年3月8日,沙特当局采取了封锁策略以控制疫情。本研究的目的是确定沙特阿拉伯封锁策略各阶段的有效性及其对COVID-19疫情基本再生数(R0)的影响。
沙特阿拉伯COVID-19疫情的时间线分为三个时间间隔。(2020年)用于估计封锁各阶段社区流动性的变化。根据沙特卫生部的每日报告,使用易感、感染和康复(SIR)模型每天计算COVID-19疫情的基本再生数(R0)。这是一个基于感染率、隔离率以及确诊率来确定病毒传播情况的标准系统。使用单向方差分析检验比较每个时间间隔内计算出的R0的平均值。
封锁不同阶段的平均值之间无统计学显著差异(P>0.05)。此外,第二个时间间隔的平均R0值比社区流动性自由的初始时间间隔高0.09。此外,全面封锁的第三个时间间隔的平均R0值比初始时间间隔高0.28。
尽早实施封锁策略并结合其他社交距离策略有助于在传染病爆发的早期阶段控制疫情。持续评估此类策略的有效性可为决策者提供在考虑其经济影响时证明其应用合理性所需的宝贵信息。