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颈部疣状癌合并毛母细胞瘤1例罕见病例报告及文献复习

A Rare Case of Verrucous Carcinoma and Trichoblastoma of the Neck: A Case Report and Literature Review.

作者信息

Brito Yesenia, Zubair Samira, Taki El-Din Zaid, Mwaniki Janice, Nair Ameya, Tiesenga Frederick

机构信息

Surgery, St. George's University School of Medicine, True Blue, GRD.

Surgery, Saint James School of Medicine, Arnos Vale, VCT.

出版信息

Cureus. 2023 Apr 28;15(4):e38236. doi: 10.7759/cureus.38236. eCollection 2023 Apr.

Abstract

Verrucous carcinoma (VC) is a variant of cutaneous squamous cell carcinoma. This phenomenon mainly affects the oropharynx, genitalia, and soles of the feet. VC is a well-defined, exophytic, cauliflower-like growth that is warty in nature. Trichoblastoma is a benign epithelial tumor composed of follicular germinative cells. It presents as a small, smooth, non-ulcerated, skin-colored nodule on the scalp, neck, thigh, and perianal regions. The dual presentation of verrucous carcinoma and trichoblastoma of the neck is rare. Though treatment can be achieved through surgical resection, early detection offers a good prognosis. We present the case of a 54-year-old homeless male who presented with an unusual neck mass that was initially misidentified as an abscess. Surgical debridement was performed, and histopathological analysis revealed the presence of a rare combination of VC and trichoblastoma. This report highlights the challenges of this rare presentation, which may be overlooked or misdiagnosed as an abscess.

摘要

疣状癌(VC)是皮肤鳞状细胞癌的一种变体。这种现象主要影响口咽、生殖器和脚底。VC是一种边界清晰、外生性、菜花状的生长物,本质上呈疣状。毛母细胞瘤是一种由毛囊生发细胞组成的良性上皮肿瘤。它表现为头皮、颈部、大腿和肛周区域的一个小的、光滑的、无溃疡的、肤色结节。颈部疣状癌和毛母细胞瘤的双重表现很罕见。虽然可以通过手术切除进行治疗,但早期发现预后良好。我们报告了一例54岁无家可归男性的病例,该患者颈部出现异常肿块,最初被误诊为脓肿。进行了手术清创,组织病理学分析显示存在VC和毛母细胞瘤的罕见组合。本报告强调了这种罕见表现所带来的挑战,其可能被忽视或误诊为脓肿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3e1/10225068/070ab4347c59/cureus-0015-00000038236-i01.jpg

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