Huang Haiyun, Cai Yuexin, Feng Xueji, Li Yuanqing
School of Automation Science and Engineering, South China University of Technology, Guangzhou 510000, P.R.China.
Brain Computer Intelligence Research Center, Pazhou Lab, Guangzhou 510330, P.R.China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2021 Jun 25;38(3):492-497. doi: 10.7507/1001-5515.202012015.
The incidence of tinnitus is very high, which can affect the patient's attention, emotion and sleep, and even cause serious psychological distress and suicidal tendency. Currently, there is no uniform and objective method for tinnitus detection and therapy, and the mechanism of tinnitus is still unclear. In this study, we first collected the resting state electroencephalogram (EEG) data of tinnitus patients and healthy subjects. Then the power spectrum topology diagrams were compared of in the band of δ (0.5-3 Hz), θ (4-7 Hz), α (8-13 Hz), β (14-30 Hz) and γ (31-50 Hz) to explore the central mechanism of tinnitus. A total of 16 tinnitus patients and 16 healthy subjects were recruited to participate in the experiment. The results of resting state EEG experiments found that the spectrum power value of tinnitus patients was higher than that of healthy subjects in all concerned frequency bands. The -test results showed that the significant difference areas were mainly concentrated in the right temporal lobe of the θ and α band, and the temporal lobe, parietal lobe and forehead area of the β and γ band. In addition, we designed an attention-related task experiment to further study the relationship between tinnitus and attention. The results showed that the classification accuracy of tinnitus patients was significantly lower than that of healthy subjects, and the highest classification accuracies were 80.21% and 88.75%, respectively. The experimental results indicate that tinnitus may cause the decrease of patients' attention.
耳鸣的发病率非常高，它会影响患者的注意力、情绪和睡眠，甚至导致严重的心理困扰和自杀倾向。目前，耳鸣检测和治疗尚无统一且客观的方法，耳鸣的机制仍不清楚。在本研究中，我们首先收集了耳鸣患者和健康受试者的静息态脑电图（EEG）数据。然后比较了δ（0.5 - 3Hz）、θ（4 - 7Hz）、α（8 - 13Hz）、β（14 - 30Hz）和γ（31 - 50Hz）频段的功率谱拓扑图，以探究耳鸣的中枢机制。共招募了16名耳鸣患者和16名健康受试者参与实验。静息态EEG实验结果发现，耳鸣患者在所有相关频段的频谱功率值均高于健康受试者。t检验结果显示，差异显著的区域主要集中在θ和α频段的右侧颞叶，以及β和γ频段的颞叶、顶叶和前额区域。此外，我们设计了一项与注意力相关的任务实验，以进一步研究耳鸣与注意力之间的关系。结果表明，耳鸣患者的分类准确率显著低于健康受试者，最高分类准确率分别为80.21%和88.75%。实验结果表明，耳鸣可能导致患者注意力下降。
