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Cognitive impairment following chemotherapy for breast cancer: The impact of practice effect on results.乳腺癌化疗后的认知障碍:实践效应对结果的影响。
J Clin Exp Neuropsychol. 2019 Apr;41(3):290-299. doi: 10.1080/13803395.2018.1546381. Epub 2018 Nov 26.
2
From the Bottom-Up: Chemotherapy and Gut-Brain Axis Dysregulation.自下而上:化疗与肠脑轴失调
Front Behav Neurosci. 2018 May 22;12:104. doi: 10.3389/fnbeh.2018.00104. eCollection 2018.
3
Oxidative stress response induced by chemotherapy in leukemia treatment.化疗在白血病治疗中引发的氧化应激反应。
Mol Clin Oncol. 2018 Mar;8(3):391-399. doi: 10.3892/mco.2018.1549. Epub 2018 Jan 10.
4
Evaluation of plasma brain-derived neurotrophic factor levels and self-perceived cognitive impairment post-chemotherapy: a longitudinal study.化疗后评估血浆脑源性神经营养因子水平与自我感知认知障碍:一项纵向研究。
BMC Cancer. 2017 Dec 19;17(1):867. doi: 10.1186/s12885-017-3861-9.
5
Patient's Cognitive Function and Attitudes towards Family Involvement in Cancer Treatment Decision Making: A Patient-Family Caregiver Dyadic Analysis.患者认知功能与对癌症治疗决策中家庭参与的态度:患者-家庭照顾者的双元分析。
Cancer Res Treat. 2018 Jul;50(3):681-690. doi: 10.4143/crt.2017.201. Epub 2017 Jul 4.
6
The Role of Oxidative Stress in Etiopathogenesis of Chemotherapy Induced Cognitive Impairment (CICI)-"Chemobrain".氧化应激在化疗诱导的认知障碍(CICI)-“化疗脑”病因学中的作用
Aging Dis. 2016 May 27;7(3):307-17. doi: 10.14336/AD.2015.1022. eCollection 2016 May.
7
The effect of cancer treatment on cognitive function.癌症治疗对认知功能的影响。
Clin Adv Hematol Oncol. 2015 Jul;13(7):441-50.
8
Chemobrain experienced by breast cancer survivors: a meta-ethnography study investigating research and care implications.乳腺癌幸存者所经历的化疗脑:一项调查研究及护理意义的元民族志研究
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9
Prevalence, mechanisms, and management of cancer-related cognitive impairment.癌症相关认知障碍的患病率、机制及管理
Int Rev Psychiatry. 2014 Feb;26(1):102-13. doi: 10.3109/09540261.2013.864260.
10
Minimal clinically important difference (MCID) for the functional assessment of cancer therapy: cognitive function (FACT-Cog) in breast cancer patients.癌症治疗功能评估的最小临床重要差异(MCID):乳腺癌患者的认知功能(FACT-Cog)。
J Clin Epidemiol. 2014 Jul;67(7):811-20. doi: 10.1016/j.jclinepi.2013.12.011. Epub 2014 Mar 18.

化疗后、非化疗乳腺癌幸存者和非癌症患者的认知感知。

Cognitive Perception among Post-Chemotherapy, Non-Chemotherapy Breast Cancer Survivors and Non-Cancer.

机构信息

Department of Medical Surgical Nursing, Faculty of Nursing, Universitas Syiah Kuala, Banda Aceh, Indonesia.

Medical Surgical Nursing Department, Faculty of Nursing, Universitas Indonesia, Depok, East Java, Indonesia.

出版信息

Asian Pac J Cancer Prev. 2021 Jun 1;22(6):1775-1780. doi: 10.31557/APJCP.2021.22.6.1775.

DOI:10.31557/APJCP.2021.22.6.1775
PMID:34181333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8418839/
Abstract

OBJECTIVE

This study aims to compare the cognitive function perceived by post-chemotherapy breast cancer survivors, breast cancer survivors without chemotherapy, and non-cancer woman patients.

METHODS

This study was conducted by a descriptive comparative method. The respondents consisted of 82 survivors of post-chemotherapy breast cancer, 81 non-chemotherapy breast cancer survivors, and 80 non-cancer woman patients who were recruited using consecutive sampling. The data were collected from October until December 2017 by using a FACT-Cog version 3 questionnaire. Data analysis was performed by using a comparative test of Kruskal-Wallis followed by a Mann-Whitney posthoc analysis.

RESULTS

The results showed that the median of cognitive function perception in breast cancer survivors post-chemotherapy, non-chemotherapy, and non-cancerous women are 94 (52-122), 113 (53-130), and 121 (69-132), respectively. Mann-Whitney's post-hoc analysis showed a significantly different perception of cognitive function between post-chemotherapy survivors and non-chemotherapy survivors; also between post-chemotherapy survivors and non-cancer women, and between non-chemotherapy survivors with non-cancer women.

CONCLUSION

Perceived cognitive impairment, comments from others, perceived cognitive abilities, and effects on quality of life in breast cancer survivors who received chemotherapy are significantly different as compared to the survivor group without chemotherapy and non-cancerous healthy women.

摘要

目的

本研究旨在比较化疗后乳腺癌幸存者、未化疗乳腺癌幸存者和非癌症女性患者的认知功能感知。

方法

本研究采用描述性对比方法进行。研究对象包括 82 名化疗后乳腺癌幸存者、81 名非化疗乳腺癌幸存者和 80 名非癌症女性患者,采用连续抽样法招募。数据于 2017 年 10 月至 12 月期间使用 FACT-Cog 版本 3 问卷收集。采用 Kruskal-Wallis 比较检验和随后的 Mann-Whitney 事后分析进行数据分析。

结果

结果显示,化疗后乳腺癌幸存者、未化疗乳腺癌幸存者和非癌症女性的认知功能感知中位数分别为 94(52-122)、113(53-130)和 121(69-132)。Mann-Whitney 事后分析显示,化疗后幸存者与未化疗幸存者、化疗后幸存者与非癌症女性以及未化疗幸存者与非癌症女性之间的认知功能感知存在显著差异。

结论

与未接受化疗的幸存者组和非癌症健康女性相比,接受化疗的乳腺癌幸存者对认知障碍的感知、他人的评价、感知的认知能力以及对生活质量的影响存在显著差异。