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机器人辅助腹盆腔手术的证据:系统评价。

The Evidence Behind Robot-Assisted Abdominopelvic Surgery : A Systematic Review.

机构信息

McGovern Medical School at UTHealth, Houston, Texas (N.H.D., O.A.O., K.B., N.B.L., J.L.H.).

Baylor College of Medicine, Houston, Texas (M.L.).

出版信息

Ann Intern Med. 2021 Aug;174(8):1110-1117. doi: 10.7326/M20-7006. Epub 2021 Jun 29.

Abstract

BACKGROUND

Use of robot-assisted surgery has increased dramatically since its advent in the 1980s, and nearly all surgical subspecialties have adopted it. However, whether it has advantages compared with laparoscopy or open surgery is unknown.

PURPOSE

To assess the quality of evidence and outcomes of robot-assisted surgery compared with laparoscopy and open surgery in adults.

DATA SOURCES

PubMed, EMBASE, Scopus, and the Cochrane Central Register of Controlled Trials were searched from inception to April 2021.

STUDY SELECTION

Randomized controlled trials that compared robot-assisted abdominopelvic surgery with laparoscopy, open surgery, or both.

DATA EXTRACTION

Two reviewers independently extracted study data and risk of bias.

DATA SYNTHESIS

A total of 50 studies with 4898 patients were included. Of the 39 studies that reported incidence of Clavien-Dindo complications, 4 (10%) showed fewer complications with robot-assisted surgery. The majority of studies showed no difference in intraoperative complications, conversion rates, and long-term outcomes. Overall, robot-assisted surgery had longer operative duration than laparoscopy, but no obvious difference was seen versus open surgery.

LIMITATIONS

Heterogeneity was present among and within the included surgical subspecialties, which precluded meta-analysis. Several trials may not have been powered to assess relevant differences in outcomes.

CONCLUSION

There is currently no clear advantage with existing robotic platforms, which are costly and increase operative duration. With refinement, competition, and cost reduction, future versions have the potential to improve clinical outcomes without the existing disadvantages.

PRIMARY FUNDING SOURCE

None. (PROSPERO: CRD42020182027).

摘要

背景

自 20 世纪 80 年代机器人辅助手术问世以来,其使用量大幅增加,几乎所有外科亚专业都已采用。然而,与腹腔镜或开放手术相比,它是否具有优势尚不清楚。

目的

评估机器人辅助手术与成人腹腔镜和开放手术相比的证据质量和结果。

资料来源

从建库至 2021 年 4 月,检索了 PubMed、EMBASE、Scopus 和 Cochrane 中央对照试验注册库。

研究选择

比较机器人辅助腹腔盆腔手术与腹腔镜、开放手术或两者的随机对照试验。

资料提取

两名审查员独立提取了研究数据和偏倚风险。

资料综合

共纳入 50 项研究,涉及 4898 例患者。在报道 Clavien-Dindo 并发症发生率的 39 项研究中,有 4 项(10%)显示机器人辅助手术的并发症较少。大多数研究显示术中并发症、中转率和长期结果无差异。总体而言,机器人辅助手术的手术时间长于腹腔镜手术,但与开放手术相比无明显差异。

局限性

纳入的外科亚专业之间和内部存在异质性,因此无法进行荟萃分析。一些试验可能没有足够的能力来评估结果的相关差异。

结论

目前,现有的机器人平台没有明显的优势,因为它们成本高昂且会增加手术时间。随着技术的改进、竞争和成本降低,未来的版本有可能在不产生现有劣势的情况下改善临床结果。

主要资金来源

无。(PROSPERO:CRD42020182027)。

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