精囊孤立性纤维瘤：系统文献回顾及病例报告。
Solitary Fibrous Tumor of the Seminal Vesicle: A Systematic Literature Review and Case Presentation.
机构信息
Department of Surgery "Pietro Valdoni", "Sapienza" University of Rome, Rome, Italy;
Department of Surgery "Pietro Valdoni", "Sapienza" University of Rome, Rome, Italy.
出版信息
In Vivo. 2021 Jul-Aug;35(4):1945-1950. doi: 10.21873/invivo.12461.
BACKGROUND/AIM: Solitary fibrous tumors (SFTs) are ubiquitous mesenchymal neoplasms that have an unpredictable biological behavior. Histological criteria for this type of malignancy are uncertain. Clinical characteristics, diagnostic and treatment options of SFTs originating in the seminal vesicle are presented in this review article.
MATERIALS AND METHODS
A systematic review including the following databases: Scopus, Embase and Medline from 1960 until the end of March 2021 was performed according to the Preferred Reporting Items for Systematic Reviews (PRISMA) guidelines.
RESULTS
We found seven patients affected with SFTs of seminal vesicle, in which we added our own case, making a total of 8 patients. Mean age at presentation was 55±7 years. Mean size of the SFTs was 9±2 cm and the right seminal vesicle was preferentially involved. The majority of patients were symptomatic and presenting symptoms were hematuria, dysuria, hematospermia, urinary increased frequency and urgency. Abdominal ultrasonography, computed tomography (CT) scan, and magnetic resonance (MRI) were the diagnostic tools. Trans-rectal ultrasound-guided core biopsy was also used. Seven (87%) patients had open surgery. Adjuvant radiotherapy after R0 resection was used in 1 patient.
CONCLUSION
The treatment of SFTs located in the seminal vesicle necessitates a radical surgical resection to obtain acceptable results in terms of local recurrence and distant metastases.
背景/目的：孤立性纤维瘤（SFT）是一种普遍存在的间叶性肿瘤，具有不可预测的生物学行为。这种恶性肿瘤的组织学标准尚不确定。本文回顾了来源于精囊的 SFT 的临床特征、诊断和治疗选择。
材料和方法
根据系统评价报告的首选项目（PRISMA）指南，对包括 Scopus、Embase 和 Medline 在内的数据库进行了系统评价，检索时间为 1960 年至 2021 年 3 月底。
结果
我们发现了 7 例精囊 SFT 患者，其中包括我们自己的病例，总共 8 例。发病时的平均年龄为 55±7 岁。SFT 的平均大小为 9±2cm，右侧精囊更易受累。大多数患者有症状，表现为血尿、排尿困难、血精、尿频和尿急。腹部超声、计算机断层扫描（CT）和磁共振（MRI）是诊断工具。经直肠超声引导下核心活检也被应用。7（87%）例患者接受了开放性手术。1 例患者在 RO 切除术后接受辅助放疗。
结论
位于精囊的 SFT 的治疗需要根治性手术切除，以获得可接受的局部复发和远处转移结果。
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