Tropical Diseases Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Trans R Soc Trop Med Hyg. 2022 Feb 1;116(2):148-156. doi: 10.1093/trstmh/trab096.
Scabies causes intense itching and skin lesions. A small number of studies have shown that scabies impacts health-related quality of life (HRQoL), but no studies have been conducted in the Pacific region. We assessed the impact of scabies on HRQoL in a high-prevalence setting using the Children's Dermatology Life Quality Index (CDLQI) and Dermatology Life Quality Index (DLQI). We also assessed the validity of these tools in a Pacific Island population.
The study was conducted in the Solomon Islands. Participants with and without skin disease were randomly selected. HRQoL indices were scored on a scale of 0-30.
We surveyed 1051 adults (91 with scabies) and 604 children (103 with scabies). Scabies had a small impact on HRQoL, with a median DLQI score of 2 (interquartile range [IQR] 0-6) and a CDLQI score of 2 (IQR 0-4). Scores increased linearly with severity. The greatest impact on QoL was due to itch, sleep disturbance and impacts on education and employment.
Scabies has a small but measurable impact on HRQoL. The DLQI and CDLQI scores were discriminated between the skin-related QoL of patients with scabies and the control group, indicating that these tools are appropriate to measure skin-related QoL in the Solomon Islands.
疥疮会引起剧烈瘙痒和皮肤损伤。少数研究表明疥疮会影响健康相关生活质量（HRQoL），但在太平洋地区尚未开展相关研究。我们使用儿童皮肤病生活质量指数（CDLQI）和皮肤病生活质量指数（DLQI）评估了高流行地区疥疮对 HRQoL 的影响。我们还评估了这些工具在太平洋岛屿人群中的有效性。
该研究在所罗门群岛进行。随机选择有和没有皮肤病的参与者。HRQoL 指数的评分范围为 0-30。
我们调查了 1051 名成年人（91 名患有疥疮）和 604 名儿童（103 名患有疥疮）。疥疮对 HRQoL 的影响较小，DLQI 中位数为 2（四分位距 [IQR] 0-6），CDLQI 中位数为 2（IQR 0-4）。评分随严重程度线性增加。对生活质量的最大影响是由于瘙痒、睡眠障碍以及对教育和就业的影响。
疥疮对 HRQoL 有一定但可衡量的影响。DLQI 和 CDLQI 评分可区分患有疥疮的患者和对照组的皮肤相关生活质量，表明这些工具适合在所罗门群岛测量皮肤相关的生活质量。
