Institute for Systems Biology, Seattle, WA, USA.
European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Cambridge, UK.
Nat Methods. 2021 Jul;18(7):768-770. doi: 10.1038/s41592-021-01184-6. Epub 2021 Jun 28.
Mass spectra provide the ultimate evidence to support the findings of mass spectrometry proteomics studies in publications, and it is therefore crucial to be able to trace the conclusions back to the spectra. The Universal Spectrum Identifier (USI) provides a standardized mechanism for encoding a virtual path to any mass spectrum contained in datasets deposited to public proteomics repositories. USI enables greater transparency of spectral evidence, with more than 1 billion USI identifications from over 3 billion spectra already available through ProteomeXchange repositories.
质谱为支持出版物中质谱蛋白质组学研究结果提供了最终证据，因此能够追溯结论到相应的光谱至关重要。通用谱标识符（USI）为编码公共蛋白质组学存储库中包含的任何数据集的质谱的虚拟路径提供了标准化机制。USI 使光谱证据更加透明，通过 ProteomeXchange 存储库已经有超过 30 亿个光谱的 10 多亿个 USI 鉴定。
