Jia Jing, Kong Fei, Xin Xueling, Liang Jiwei, Xin Hualei, Dong Liyan, Jiang Fachun
Department of Acute Infectious Disease, Qingdao Centre for Disease Control and Prevention, Qingdao Institute of Prevention Medicine, Qingdao, Shandong, China.
Sinopec Research Institute of Safety Engineering, Qingdao, Shandong, China.
Iran J Public Health. 2021 May;50(5):999-1008. doi: 10.18502/ijph.v50i5.6117.
In China, hand, foot, and mouth disease (HFMD) outbreaks have become an important issue recent years. We analyzed the epidemiological characteristics of HFMD outbreaks in Qingdao during 2009-2018, and provided evidences for prevention and control of the disease.
Data were analyzed by descriptive analysis and correlation analysis, and throat swabs were detected for enterovirus RNA using RT-PCR.
Overall, 116 HFMD outbreaks were reported in Qingdao during 2009-2018, with the epidemic of the outbreaks exhibiting a decreasing tendency. The characteristics of outbreaks presented two patterns, including two-peak pattern and rural area to urban-rural fringe area to urban areas pattern. Male patients were predominant in these outbreaks. The location of the outbreaks changed from nursery to community. Non-EV71/CA16 enteroviruses were gradually becoming predominant enteroviruses serotypes. The durations of outbreaks were positively correlated with response times and the number of cases.
The epidemiological characteristics analysis of HFMD outbreaks could provide a scientific basis for the prevention and control the disease. Reporting and handling promptly are the keys to control epidemic outbreaks of HFMD.
近年来，手足口病（HFMD）疫情在中国已成为一个重要问题。我们分析了2009 - 2018年青岛市手足口病疫情的流行病学特征，为该病的预防和控制提供依据。
采用描述性分析和相关性分析方法对数据进行分析，并使用逆转录聚合酶链反应（RT-PCR）检测咽拭子中的肠道病毒RNA。
总体而言，2009 - 2018年青岛市共报告116起手足口病疫情，疫情呈下降趋势。疫情特征呈现两种模式，包括双峰模式和从农村到城乡结合部再到城市的模式。这些疫情中男性患者居多。疫情发生地点从托幼机构转变为社区。非肠道病毒71型/柯萨奇病毒A16型肠道病毒逐渐成为主要的肠道病毒血清型。疫情持续时间与响应时间和病例数呈正相关。
手足口病疫情的流行病学特征分析可为该病的预防和控制提供科学依据。及时报告和处理是控制手足口病疫情爆发的关键。
