Washington University in Saint Louis, Saint Louis, Missouri 63130, United States.
Org Lett. 2021 Jul 16;23(14):5440-5444. doi: 10.1021/acs.orglett.1c01675. Epub 2021 Jun 29.
Construction of larger molecular libraries on an addressable microelectrode array requires a method for recovering and characterizing molecules from the surface of any electrode in the array. This method must be orthogonal to the synthetic strategies needed to build the array. We report here a method for achieving this goal that employs the site-selective dihydroxylation reaction of a simple olefin.
在可寻址微电极阵列上构建更大的分子库需要一种从阵列中任何电极表面回收和表征分子的方法。该方法必须与构建阵列所需的合成策略正交。我们在这里报告了一种实现这一目标的方法，该方法采用了简单烯烃的选择性双羟基化反应。
