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急性护理医院中的新冠死亡率:患者因素与放弃重症监护病房的决策之间的关联。

Covid-19 Mortality in an Acute Care Hospital: Association of Patient Factors With Decision to Forego the Intensive Care Unit.

机构信息

Department of Medicine, Annapolis, MD, USA.

589981Luminis Health Research Institute, Luminis Health, Annapolis, MD, USA.

出版信息

Am J Hosp Palliat Care. 2022 Apr;39(4):481-486. doi: 10.1177/10499091211028849. Epub 2021 Jun 29.

Abstract

BACKGROUND

Public awareness of the large mortality toll of COVID-19 particularly among elderly and frail persons is high. This public awareness represents an enhanced opportunity for early and urgent goals-of-care discussions to reduce medically ineffective care.

OBJECTIVE

To assess the end-of-life experiences of hospitalized patients dying of COVID-19 with respect to identifying the clinical factors associated with utilization or non-utilization of the ICU.

METHODS

Retrospective cohort study of hospital outcomes using electronic medical records and individual chart review from March 15, 2020 to October 15, 2020 of every patient with a COVID-19 diagnosis who died or was admitted to hospice while hospitalized. Logistic regression multivariate analysis was used to identify the clinical and demographic factors associated with non-utilization of the ICU.

RESULTS

133/749 (18%) of hospitalized COVID-19 patients died or were admitted to hospice as a result of COVID-19. Of the 133, 66 (49.6%) had no ICU utilization. In multivariate analysis, the significant patient factors associated with non-ICU utilization were increasing age, normal body mass index, and the presence of an advanced directive calling for limited life sustaining therapies. Race and residence at time of admission (home vs. facility) were significant only in the unadjusted analyses but not in adjusted. Gender was not significant in either form of analyses.

CONCLUSION

Goals of care discussions performed by an augmented palliative care team and other bedside clinicians had renewed urgency during COVID-19. Large percentages of patients and surrogates, perhaps motivated by public awareness of poor outcomes, opted not to utilize the ICU.

摘要

背景

公众对 COVID-19 死亡率,尤其是老年人和体弱者死亡率的认识很高。这种公众意识为尽早进行紧急的目标治疗讨论提供了机会,以减少无效的医疗护理。

目的

评估因 COVID-19 住院死亡患者的临终体验,以确定与 ICU 使用或不使用相关的临床因素。

方法

这是一项回顾性队列研究,使用电子病历和 2020 年 3 月 15 日至 2020 年 10 月 15 日期间每个 COVID-19 诊断患者的个人图表审查,这些患者在住院期间因 COVID-19 死亡或转入临终关怀。采用多变量逻辑回归分析来确定与 ICU 不使用相关的临床和人口统计学因素。

结果

749 名住院 COVID-19 患者中,有 133 名(18%)因 COVID-19 死亡或转入临终关怀。在这 133 名患者中,有 66 名(49.6%)未使用 ICU。多变量分析显示,与不使用 ICU 相关的重要患者因素包括年龄增加、正常体重指数和存在限制生命维持治疗的高级指令。入院时的种族和居住地(家庭与机构)仅在未调整分析中具有显著性,但在调整分析中则不具有显著性。性别在任何形式的分析中均不显著。

结论

在 COVID-19 期间,由扩充的姑息治疗团队和其他床边临床医生进行的目标治疗讨论变得更加紧迫。很大比例的患者和代理人,也许是由于公众对不良结局的认识,选择不使用 ICU。

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