Apiyo Mirriam, Olum Ronald, Kabuye Amina, Khainza Betty, Amate Anne M, Byabashaija Vittal, Nomujuni Derrick, Sebbaale Kato, Senfuka Peter, Kazibwe Simon, Sharma Gurav, Davidson Lindsay, Bongomin Felix
Case Hospital, Kampala, Uganda.
Department of Internal Medicine, St. Francis Hospital Nsambya, Kampala, Uganda.
Interdiscip Perspect Infect Dis. 2022 Jun 8;2022:5477790. doi: 10.1155/2022/5477790. eCollection 2022.
Data on clinical outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19) in private health facilities in Uganda is scarce. We conducted a retrospective cohort study of patients hospitalized with COVID-19 at Case Hospital, Kampala, Uganda, between June 2020 and September 2021. Data of 160 participants (median age 45 years (interquartile range [IQR]: 37-57) and 63.5% male) was analyzed. Seventy-seven (48.1%) participants had non-severe, 18 (11.3%) severe, and 83 (51.9%) critical COVID-19 illness. In 62 participants with chest computed tomography findings, 54 (87%) had bilateral disease, with 22 (35%) having ground-glass opacities. The median duration of hospitalization was 5 days (IQR: 3-9 days). Overall, 18 (11.3%) participants died. Survival at 14 and 28 days was 89% and 72%, respectively. Factors strongly associated with all-cause mortality were as follows: age >50 years (odds ratio [OR]: 8.6, 95% confidence interval [CI]: 1.1-69.2, and =0.042), having at least 1 comorbidity (OR: 3.2, 95% CI: 1.1-8.9, and =0.029), hypertension (OR: 3.2, 95% CI: 1.2-8.6, and =0.024), diabetes mellitus (OR: 2.9, 95% CI: 1.0-8.5, and=0.056), and oxygen saturation <92% (OR: 5.1, 95% CI: 1.8-14.4, and =0.002). In this private health facility, mortality was about 1 in 10 patients, and more people presented with critical illness in the second wave of the pandemic, and most deaths occurred after 2 weeks of hospitalization.
关于乌干达私立医疗机构中因2019冠状病毒病（COVID-19）住院患者的临床结局数据稀缺。我们对2020年6月至2021年9月期间在乌干达坎帕拉的凯斯医院因COVID-19住院的患者进行了一项回顾性队列研究。分析了160名参与者的数据（中位年龄45岁（四分位间距[IQR]：37 - 57），63.5%为男性）。77名（48.1%）参与者患有非重症COVID-19，18名（11.3%）患有重症，83名（51.9%）患有危重症COVID-19。在62名有胸部计算机断层扫描结果的参与者中，54名（87%）有双侧病变，其中22名（35%）有磨玻璃影。住院中位时长为5天（IQR：3 - 9天）。总体而言，18名（11.3%）参与者死亡。14天和28天的生存率分别为89%和72%。与全因死亡率密切相关的因素如下：年龄>50岁（比值比[OR]：8.6，95%置信区间[CI]：1.1 - 69.2，P = 0.042）、至少有一种合并症（OR：3.2，95% CI：1.1 - 8.9，P = 0.029）、高血压（OR：3.2，95% CI：1.2 - 8.6，P = 0.024）、糖尿病（OR：2.9，95% CI：1.0 - 8.5，P = 0.056）以及氧饱和度<92%（OR：5.1，95% CI：1.8 - 14.4，P = 0.002）。在这家私立医疗机构中，死亡率约为十分之一，在疫情第二波中更多人表现为危重症，且大多数死亡发生在住院2周后。
