Department of Orthopedics, Lanzhou University Second Hospital, Lanzhou, PR China.
Key Laboratory of Bone and Joint Disease Research of Gansu Province, Lanzhou, PR China.
Br J Neurosurg. 2024 Jun;38(3):562-567. doi: 10.1080/02688697.2021.1923654. Epub 2021 Jun 29.
To compare the new zero-profile (Zero-P) fusion cage with regular cage and plate (CP) in the treatment of anterior cervical single-level cervical degenerative diseases.
Patients operated from January 2013 to August 2018 were enrolled. They were divided into the Zero-P group ( = 74 cases) and CP groups ( = 116 cases). Follow-up assessment was at 1, 3, 12, and 24 months after surgery, including the incidence of dysphagia, visual analogue scale (VAS) score, Japanese orthopaedic association (JOA)score, C2-C7 Cobb angle, intervertebral disc height (IDH) and adjacent joint degeneration.
The operation time and blood loss of patients in Zero-P group were less than those in the CP group, and there was no difference in hospitalization time. All 190 patients were followed up for 24 to 72 months, with an average of 35.29 months. In terms of clinical outcomes, vas and JOA scores of the two groups were significantly improved at one month and the last follow-up. The incidence of dysphagia in the Zero-P group was lower than that in the CP group. On radiological effects, Cobb angle and IDH showed significant correction in both groups, but the degeneration rate of adjacent joints in the Zero-P group was lower than the CP group.
In ACDF, the clinical and radiological results of Zero-P and CP devices are satisfactory, but Zero-P cage may be superior in operation time, blood loss, the incidence of dysphagia and adjacent joint degeneration.
比较新型零切迹(Zero-P)融合 cage 与常规 cage 和板(CP)治疗单节段颈前路颈椎退行性疾病的效果。
纳入 2013 年 1 月至 2018 年 8 月间接受手术的患者。根据治疗方式分为 Zero-P 组(n=74)和 CP 组(n=116)。术后 1、3、12 和 24 个月进行随访评估,包括吞咽困难发生率、视觉模拟量表(VAS)评分、日本矫形协会(JOA)评分、C2-C7 Cobb 角、椎间盘高度(IDH)和邻近关节退变情况。
Zero-P 组的手术时间和出血量均少于 CP 组,而住院时间无差异。190 例患者均获得 24 至 72 个月(平均 35.29 个月)随访。在临床结果方面,两组的 VAS 和 JOA 评分均在术后 1 个月和末次随访时显著改善。Zero-P 组的吞咽困难发生率低于 CP 组。在影像学效果方面,两组 Cobb 角和 IDH 均有显著矫正,但 Zero-P 组邻近关节退变发生率低于 CP 组。
在 ACDF 中,Zero-P 和 CP 装置的临床和影像学结果均令人满意,但 Zero-P cage 在手术时间、出血量、吞咽困难发生率和邻近关节退变方面可能更具优势。