Staffa Steven J, Kohane Daniel S, Zurakowski David
Department of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Harvard Medical School, Boston Massachusetts 02115, United States.
Nano Lett. 2021 Jul 14;21(13):5457-5460. doi: 10.1021/acs.nanolett.1c01894. Epub 2021 Jun 29.
Interactions between nanoformulations delivering two or more drugs-or a drug and some other therapeutic modality-are often described as synergistic. In fact, synergy is a specific term of art, with important therapeutic implications. The term is often misused in the nanoscience literature. Here we discuss what synergy is and an approach to demonstrating it rigorously.
递送两种或更多种药物——或一种药物与某种其他治疗方式——的纳米制剂之间的相互作用通常被描述为具有协同作用。事实上，协同作用是一个具有重要治疗意义的特定专业术语。该术语在纳米科学文献中经常被误用。在此，我们将讨论协同作用是什么以及一种严格证明它的方法。
