Inhibition of lysine methyltransferase G9a/GLP reinstates long-term synaptic plasticity and synaptic tagging/capture by facilitating protein synthesis in the hippocampal CA1 area of APP/PS1 mouse model of Alzheimer's disease.
作者信息
Han Javan Lee Tze, Pang Karen Ka Lam, Ang Sheila Rui Xia, Sharma Mahima, Sajikumar Sreedharan
机构信息
Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore.
Neurobiology Programme, Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore.
出版信息
Transl Neurodegener. 2021 Jun 29;10(1):23. doi: 10.1186/s40035-021-00247-0.
Abstract
摘要
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