Department of Neuropsychology, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
Department of Neurosciences and Psychiatry, University of California, San Diego, San Diego, CA, USA.
J Int Neuropsychol Soc. 2022 Jul;28(6):611-619. doi: 10.1017/S1355617721000850. Epub 2021 Jun 30.
Story memory tasks are among the most commonly used memory tests; however, research suggests they may be less sensitive to memory decline and have a weaker association with hippocampal volumes than list learning tasks. To examine its utility, we compared story memory to other memory tests on impairment rates and association with hippocampal volumes.
Archival records from 1617 older adults (M = 74.41, range = 65-93) who completed the Wechsler Memory Scale - 4 edition (WMS-IV) Logical Memory (LM), Hopkins Verbal Learning Test - Revised (HVLT-R), and Brief Visuospatial Memory Test - Revised (BVMT-R) as part of a clinical neuropsychological evaluation were reviewed. Scores >1.5 below age-adjusted means were considered impaired, and frequency distributions were used to examine impairment rates. A subset of participants ( = 179) had magnetic resonance imaging (MRI) data that underwent image quality assessment. Partial correlations and linear regression analyses, accounting for age, education, and total intracranial volume (TIV), examined associations between memory raw scores and hippocampal volumes.
For delayed recall, nearly half of the sample was impaired on HVLT-R (48.8%) and BVMT-R (46.1%), whereas a little more than a third was impaired on LM (35.7%). Better performance on all three measures was related to larger hippocampal volumes ('s =. 26-.43, < .001). Individually adding memory scores to regression models predicting hippocampal volumes improved the model fit for all measures.
Despite findings suggesting that story memory is less sensitive to memory dysfunction, it was not differentially associated with hippocampal volumes compared to other memory measures. Results support assessing memory using different formats and modalities in older adults.
故事记忆任务是最常用的记忆测试之一；然而，研究表明，与列表学习任务相比，它们可能对记忆衰退的敏感性较低，与海马体体积的相关性也较弱。为了检验其效用，我们比较了故事记忆与其他记忆测试在损伤率和与海马体体积的相关性方面的表现。
对 1617 名年龄较大的成年人（M = 74.41，范围为 65-93）的档案记录进行了回顾，这些成年人在临床神经心理学评估中完成了韦氏记忆量表第四版（WMS-IV）逻辑记忆（LM）、霍普金斯言语学习测验修订版（HVLT-R）和简短视觉空间记忆测验修订版（BVMT-R）。得分低于年龄调整平均值 1.5 分被认为受损，频率分布用于检查受损率。一部分参与者（n = 179）有磁共振成像（MRI）数据，这些数据经过了图像质量评估。偏相关和线性回归分析，考虑了年龄、教育程度和总颅内体积（TIV），检验了记忆原始分数与海马体体积之间的相关性。
对于延迟回忆，近一半的样本在 HVLT-R（48.8%）和 BVMT-R（46.1%）上受损，而略多于三分之一的样本在 LM（35.7%）上受损。所有三种测量方法的表现越好，海马体体积越大（r 的值为.26-.43，p 值均<.001）。单独将记忆得分添加到预测海马体体积的回归模型中，提高了所有测量方法的模型拟合度。
尽管有研究表明故事记忆对记忆功能障碍的敏感性较低，但与其他记忆测量方法相比，它与海马体体积的相关性并没有差异。研究结果支持在老年人中使用不同的格式和模式评估记忆。
