一名日本女性患罕见的非典型骨髓结节病，无肺部受累。
A rare case of atypical bone marrow sarcoidosis without pulmonary involvement in a Japanese woman.
作者信息
Iwata Maki, Kodama Tatsuya, Takeo Hiroaki, Mataki Norikazu
机构信息
Internal Medicine, Mishuku Hospital, Megro, Japan
Department of Internal Medicine, Self-Defence Forces Central Hospital, Setagaya, Japan.
出版信息
BMJ Case Rep. 2021 Jun 29;14(6):e240577. doi: 10.1136/bcr-2020-240577.
Abstract
Sarcoidosis is a systemic granulomatous disease of unknown origin characterised by the presence of non-caseating granulomatous lesions. Extrapulmonary sarcoidosis with bone marrow involvement is rare and even more so without pulmonary involvement. Here, we describe a case of 69-year-old woman diagnosed as having bone marrow and hepatic sarcoidosis without pulmonary involvement based on F-fluorodeoxyglucose positron emission tomography findings. She was successfully treated with systemic glucocorticoid therapy.
摘要
结节病是一种病因不明的全身性肉芽肿性疾病，其特征为存在非干酪样肉芽肿性病变。肺外结节病合并骨髓受累较为罕见，而无肺部受累的情况则更为少见。在此，我们报告一例69岁女性患者，根据氟脱氧葡萄糖正电子发射断层扫描结果，诊断为无肺部受累的骨髓和肝脏结节病。她通过全身糖皮质激素治疗获得成功治愈。
相似文献
1
A rare case of atypical bone marrow sarcoidosis without pulmonary involvement in a Japanese woman.一名日本女性患罕见的非典型骨髓结节病，无肺部受累。
BMJ Case Rep. 2021 Jun 29;14(6):e240577. doi: 10.1136/bcr-2020-240577.
2
Atypical sarcoidosis: case reports and review of the literature.非典型结节病：病例报告及文献综述
Eur Rev Med Pharmacol Sci. 2009 Mar;13 Suppl 1:37-44.
3
Granulomatous lesions in bone marrow: clinicopathologic findings and significance in a study of 48 cases.骨髓内的肉芽肿性病变：48 例研究中的临床病理表现及意义。
Eur J Intern Med. 2013 Jul;24(5):468-73. doi: 10.1016/j.ejim.2012.11.008. Epub 2013 Feb 13.
4
Bone and bone marrow involvement in sarcoidosis.结节病中的骨骼和骨髓受累情况。
Rheumatol Int. 2015 Nov;35(11):1917-24. doi: 10.1007/s00296-015-3341-y. Epub 2015 Aug 7.
5
Fluorine-18 fluorodeoxyglucose with positron emission tomography revealed bone marrow involvement in sarcoidosis patients with anaemia.氟-18 氟代脱氧葡萄糖正电子发射断层扫描显示贫血的结节病患者骨髓受累。
Respiration. 2010;79(1):25-31. doi: 10.1159/000204901. Epub 2009 Feb 25.
6
A Rare Case of Relapsed Sarcoidosis Presenting As Severe Thrombocytopenia Associated With Intracerebral Hemorrhage Due to Bone Marrow Involvement.一例罕见的复发性结节病，表现为严重血小板减少症并因骨髓受累导致脑出血。
Cureus. 2023 Apr 22;15(4):e37973. doi: 10.7759/cureus.37973. eCollection 2023 Apr.
7
Pancreatic involvement detected with (18)F-FDG PET/CT in disseminated sarcoidosis.（18）F-FDG PET/CT检测播散性结节病中的胰腺受累情况。
Rev Esp Med Nucl. 2011 Jan-Feb;30(1):29-32. doi: 10.1016/j.remn.2010.04.013. Epub 2010 Jul 16.
8
F-FDG PET/CT in bone sarcoidosis: an observational study.氟代脱氧葡萄糖正电子发射断层显像/计算机断层扫描在骨结节病中的应用：一项观察性研究。
Clin Rheumatol. 2020 Sep;39(9):2727-2734. doi: 10.1007/s10067-020-05022-6. Epub 2020 Mar 20.
9
[Sarcoidosis].[结节病]
Ugeskr Laeger. 2018 Aug 20;180(34).
10
Cardiac magnetic resonance imaging-indeterminate/negative cardiac sarcoidosis revealed by F-fluorodeoxyglucose-positron emission tomography: two case reports and a review of the literature.F-氟脱氧葡萄糖正电子发射断层扫描显示的心脏磁共振成像不确定/阴性心脏结节病：两例报告并文献复习
J Med Case Rep. 2017 Oct 20;11(1):291. doi: 10.1186/s13256-017-1453-6.
引用本文的文献
1
Extrapulmonary Sarcoidosis With Multi-Organ Involvement Presenting Primarily as Hypercalcemia.以高钙血症为主要表现的多器官受累的肺外结节病
Cureus. 2023 Jan 9;15(1):e33562. doi: 10.7759/cureus.33562. eCollection 2023 Jan.
本文引用的文献
1
Diagnosis and Detection of Sarcoidosis. An Official American Thoracic Society Clinical Practice Guideline.结节病的诊断与检测：美国胸科学会临床实践指南
Am J Respir Crit Care Med. 2020 Apr 15;201(8):e26-e51. doi: 10.1164/rccm.202002-0251ST.
2
Clinical Features of Extrapulmonary Sarcoidosis Without Lung Involvement.肺外结节病的临床特征。
Chest. 2018 Aug;154(2):349-356. doi: 10.1016/j.chest.2018.02.003. Epub 2018 Feb 14.
3
Diagnostic Utility of Angiotensin-Converting Enzyme in Sarcoidosis: A Population-Based Study.血管紧张素转换酶在结节病中的诊断效用：一项基于人群的研究。
Lung. 2016 Feb;194(1):91-5. doi: 10.1007/s00408-015-9826-3. Epub 2015 Nov 13.
4
Conventional markers in determination of activity of sarcoidosis.结节病活动度测定中的传统标志物。
Int Immunopharmacol. 2015 Mar;25(1):174-9. doi: 10.1016/j.intimp.2015.01.015. Epub 2015 Jan 23.
5
F-18 FDG PET/CT for detecting bone and bone marrow involvement in sarcoidosis patients.F-18 FDG PET/CT 检测结节病患者骨骼和骨髓受累。
Clin Nucl Med. 2012 Jan;37(1):21-5. doi: 10.1097/RLU.0b013e3182335f9b.
6
Pulmonary sarcoidosis.肺结节病
Clin Chest Med. 2004 Sep;25(3):521-30, vi. doi: 10.1016/j.ccm.2004.04.006.
7
Serum soluble interleukin-2 receptor measurement in patients with sarcoidosis: a clinical evaluation.结节病患者血清可溶性白细胞介素-2受体检测：一项临床评估
Chest. 2003 Jul;124(1):186-95. doi: 10.1378/chest.124.1.186.
8
Bone sarcoidosis.骨结节病
Curr Opin Rheumatol. 2000 Jul;12(4):321-30. doi: 10.1097/00002281-200007000-00016.
9
Serum angiotensin converting enzyme in sarcoidosis--its value in present clinical practice.结节病中的血清血管紧张素转换酶——其在当前临床实践中的价值
Ann Clin Biochem. 1989 Jan;26 ( Pt 1):13-8. doi: 10.1177/000456328902600102.
10
Bone and joint sarcoidosis.骨与关节结节病
Semin Arthritis Rheum. 1976 Aug;6(1):53-81. doi: 10.1016/s0049-0172(76)80005-4.
Zotero 插件