非酒精性脂肪性肝病与感染的相关性研究，中国大理市。
Association between nonalcoholic fatty liver disease and infection in Dali City, China.
机构信息
From the Department of Gastroenterology (Yan, Li), from the Department of Clinical Laboratory (Yu, Zhao), the First Affiliated Hospital, Dali University, and from the Department of Hematology (Li), BaoShan People's Hospital, Dali, China.
出版信息
Saudi Med J. 2021 Jul;42(7):735-741. doi: 10.15537/smj.2021.42.7.20210040.
OBJECTIVES
To investigate whether gastric ) infection is associated with the progress of nonalcoholic fatty liver disease (NAFLD) in Dali city, China.
METHODS
One thousand and one hundred eighty-five adults who had visited a health examination center were enrolled. Nonalcoholic fatty liver disease and infection were assessed by abdominal color ultrasound and C-urea breath test, respectively. Serum lipid metabolic indices were compared between NAFLD subjects without and with infection.
RESULTS
The prevalence rate of NAFLD for the entire study population (n=1185) was 44.6% (n=529), including 167 women and 362 men. Among 529 NAFLD subjects, was confirmed as a significant and independent risk factor for NAFLD (95% CI 1.02-1.79, =0.036, OR =1.35). Compared with non-infected individuals (n=721), higher contents of LDL-C (=0.012) along with TC (=0.014) were also observed in i-infected individuals (n=464).
CONCLUSION
A positive correlation is identified between infection and NAFLD.
目的
探讨中国大理市人群中胃部感染与非酒精性脂肪性肝病（NAFLD）进展的关系。
方法
共纳入 1185 名曾到健康体检中心就诊的成年人。采用腹部彩色超声和 C-尿素呼气试验分别评估非酒精性脂肪性肝病和 感染。比较 NAFLD 患者中无感染和有感染患者的血清脂质代谢指标。
结果
整个研究人群（n=1185）的 NAFLD 患病率为 44.6%（n=529），包括 167 名女性和 362 名男性。在 529 名 NAFLD 患者中， 感染被确认为 NAFLD 的显著独立危险因素（95%CI 1.02-1.79，=0.036，OR=1.35）。与未感染个体（n=721）相比，感染个体（n=464）的 LDL-C（=0.012）和 TC（=0.014）含量也更高。
结论
感染与 NAFLD 之间存在正相关关系。
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