A型肉毒杆菌神经毒素治疗腮腺瘘和味觉出汗综合征

Management of parotid fistula and Frey's syndrome with Botulinum neurotoxin type A.

作者信息

Chowdhury Ripon, Roy Dev, Roy Abhimanyu

机构信息

Department of Oral and Maxillofacial Pathology, Hi-Tech Dental College and Hospital, Bhubaneswar, Odisha, India.

Department of ENT, Rabindranath Tagore International Institute of Cardiac Sciences, Kolkata, West Bengal, India.

出版信息

Natl J Maxillofac Surg. 2021 Jan-Apr;12(1):106-108. doi: 10.4103/njms.NJMS_72_20. Epub 2021 Mar 16.

DOI:10.4103/njms.NJMS_72_20

PMID:34188411

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8191560/

Abstract

The common cause of parotid fistula is parotid gland surgery and is frequently due to injury to the gland rather than to the duct. The frequency of postparotidectomy fistula is 14%. Other causes include facial trauma, congenital anomalies of the parotid gland, malignancies originating from the parotid gland and infections. Although there are several options for the treatment of parotid fistula and Frey's syndrome, very few treatment options are deemed optimal. The use of Botulinum A neurotoxin as a conservative method of treatment for parotid fistula and Frey's syndrome is a recent and evolving concept.

摘要

腮腺瘘的常见病因是腮腺手术，且常常是由于腺体损伤而非导管损伤所致。腮腺切除术后瘘的发生率为14%。其他病因包括面部创伤、腮腺先天性异常、源自腮腺的恶性肿瘤及感染。尽管治疗腮腺瘘和 Frey 综合征有多种选择，但很少有治疗方案被认为是最佳的。使用A型肉毒杆菌神经毒素作为腮腺瘘和 Frey 综合征的保守治疗方法是一个新出现且不断发展的概念。