Jannu Anubhav, Rao Gautam, Kulambi Mithun, Talkal Arun Kumar, Suma M S, Deepa K K, Srinivas Rachana
Department of Oral and Maxillofacial Surgery, Subbaiah Institute of Medical and Dental Sciences, Shimoga, Karnataka, India.
Department of Oral and Maxillofacial Pathology, Subbaiah Institute of Medical and Dental Sciences, Shimoga, Karnataka, India.
Natl J Maxillofac Surg. 2021 Jan-Apr;12(1):124-127. doi: 10.4103/njms.NJMS_102_19. Epub 2021 Mar 16.
Clear cell odontogenic carcinoma is a rare, infrequent, aggressive in nature, locally reoccurring odontogenic tumor with a tendency of distant metastasis, occurring during to 4 to 6 decades with a mostly female predilection. Histologically, it is characterized by sheets and islands of vacuolated/clear cells. Till date, only 74 cases have been reported in the literature. We present a case of 45-year-old woman with a tumor mass extending from the maxillary right first premolar till the third molar region measuring 4 cm × 4 cm. The diagnosis was given based on the histopathological findings. Being locally aggressive, the reported data and understanding of this infrequent tumor needs to be strengthened by reporting new cases, and it also demands to be distinguished from other primary and metastatic clear cell tumors of the head-and-neck region.
透明细胞牙源性癌是一种罕见、不常见、具有侵袭性、易局部复发且有远处转移倾向的牙源性肿瘤，发病年龄多在4至6十岁，女性多见。组织学上，其特征为成片和岛状的空泡状/透明细胞。迄今为止，文献中仅报道了74例。我们报告一例45岁女性患者，肿瘤肿块从右上颌第一前磨牙延伸至第三磨牙区域，大小为4 cm×4 cm。诊断基于组织病理学检查结果。由于其具有局部侵袭性，需要通过报告新病例来加强对这种罕见肿瘤的现有数据了解，同时也需要将其与头颈部其他原发性和转移性透明细胞肿瘤相鉴别。
