Hansen L S, Eversole L R, Green T L, Powell N B
Head Neck Surg. 1985 Nov-Dec;8(2):115-23. doi: 10.1002/hed.2890080208.
This report delineates the clinical and laboratory findings for a previously unreported neoplasm of putative odontogenic origin. We describe the clinical, radiographic, operative, histologic, histochemical, and ultrastructural findings of the tumor in three women. All lesions were centrally located in the jaw bones, were expansile, and, except for mobile teeth and/or jaw enlargement, exhibited few symptoms. Radiographically, there was bone and tooth destruction resulting in poorly delineated margins. Microscopically, the tumors were nearly identical in that they consisted primarily of large sheets and islands of uniform vacuolated and clear cells without evidence of amyloid deposition, calcification, or glandular differentiation. One of the lesions recurred 1 1/2 years after removal without evidence of metastasis. The results, based only on these cases, suggest that this is a locally aggressive neoplasm of odontogenic origin. Casual microscopic examination of this rare neoplasm could result in misdiagnosis as a metastatic clear cell neoplasm, especially renal cell carcinoma.
本报告阐述了一种先前未报道的、推测源自牙源性的肿瘤的临床和实验室检查结果。我们描述了三名女性患者肿瘤的临床、影像学、手术、组织学、组织化学和超微结构检查结果。所有病变均位于颌骨中心，呈膨胀性生长，除牙齿松动和/或颌骨肿大外，几乎没有症状。影像学检查显示有骨质和牙齿破坏，边界不清。显微镜下，肿瘤几乎相同，主要由大片和岛屿状均匀的空泡状及透明细胞组成，无淀粉样沉积、钙化或腺性分化证据。其中一个病变在切除后1年半复发，无转移迹象。仅基于这些病例的结果表明，这是一种具有局部侵袭性的牙源性肿瘤。对这种罕见肿瘤进行随意的显微镜检查可能会误诊为转移性透明细胞瘤，尤其是肾细胞癌。
